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Maraviroc Coupon - Maraviroc 300mg tablet

maraviroc

Generic Selzentry
Used for HIV Treatment
Used for HIV Treatment

Maraviroc (Selzentry) is a medication that's used in combination with other antiretroviral (ARV) therapy to treat CCR5-tropic human immunodeficiency virus (HIV) infections. It comes as oral tablets (both generic and brand name) and solution (brand name only) for adults and children weighing over 4 pounds. Typically this medication is taken by mouth twice daily. Missing doses can make it easier for the HIV virus to change form and become resistant towards maraviroc (Selzentry). Some side effects include rash, cough, and fever. Rarely this medication can cause memory loss as well.

Last reviewed on November 4, 2024
basics-icon

What is Maraviroc (Selzentry)?

What is Maraviroc (Selzentry) used for?

How Maraviroc (Selzentry) works

Maraviroc (Selzentry) is a CCR5 antagonist, which means it blocks a protein called CCR5. CCR5 is usually found on the surface of certain immune system cells and is used by the HIV virus to infect healthy cells. By blocking CCR5, maraviroc (Selzentry) stops the virus from getting into these cells, which helps slow down HIV infection and spread in the body.

Drug Facts

Common BrandsSelzentry
Drug ClassHIV ARV
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the side effects of Maraviroc (Selzentry)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Upper respiratory tract infection (23%)
  • Cough (14%)
  • Fever (13%)
  • Dizziness (9%)
  • Trouble sleeping (8%)
  • Herpes infection (8%)
  • Changes in appetite (8%)
  • Constipation (6%)

Other Side Effects

  • Pink eye
  • Inflamed hair follicles
  • Ear infection
  • Pins and needles feeling
  • Nerve pain
  • Muscle pain
  • Changes in mood
  • Congestion

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Liver problems: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the skin or whites of the eyes, dark-colored urine, light-colored stool
  • Severe allergic reactions: facial swelling, hives, rash, itchy skin, blistering or peeling of skin, body aches, trouble breathing, mouth sores

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain

burning or stinging of the skin

chills

cough producing mucus

coughing

dizziness when getting up suddenly from a lying or sitting position

ear congestion

headache

loss of voice

pain or tenderness around the eyes and cheekbones

painful blisters on the trunk of the body

painful cold sores or blisters on the lips, nose, eyes, or genitals

sneezing

sore throat

stuffy or runny nose

tightness of the chest

trouble breathing

unusual tiredness or weakness

Less common

Arm, back, or jaw pain

black, tarry stools

blood in the urine

blurred or double vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning, dry, or itching eyes

burning, itching, and pain in the hairy areas, pus at the root of the hair

change in consciousness

chest pain, discomfort, or heaviness

choking

clay-colored stools

cold, clammy skin

confusion

dark-colored urine

diarrhea

dilated neck veins

discharge or excessive tearing

dizziness

drowsiness

earache

eye pain

fast, weak pulse

fever

frequent urge to urinate

general feeling of discomfort or illness

heavy jaw feeling

inability to speak

increased frequency of urination

irregular breathing

itching or rash

joint pain

light-colored stools

lightheadedness

loosening of a tooth

loss of appetite

loss of bladder control

loss of taste

lumps in the tongue

muscle aches, cramps, pains, spasms, or stiffness

nausea or vomiting

nervousness

noisy breathing

pain or burning during urination

pain or discomfort in the arms, jaw, back, or neck

pain, swelling, or numbness in the mouth or jaw

pale skin

pounding in the ears

redness or swelling in the ear

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

seizures

sensitivity of the eye to light

severe or sudden headache

shakiness in the legs, arms, hands, or feet

shivering

skin lumps

slow, fast, or irregular heartbeat

slurred speech

spread of cancer to the liver

stiff neck or back

stomach cramps, lumps, pain, or tenderness

sudden loss of consciousness

sweating

swelling of the face, fingers, feet, or lower legs

swollen glands

tearing

temporary blindness

trembling or shaking of the hands or feet

trouble sleeping

unable to speak

unpleasant breath odor

unsteadiness or awkwardness

unusual bleeding or bruising

vomiting of blood

warts on the genital area

watery and severe diarrhea, which may also be bloody

weakness in the arms, hands, legs, or feet

weakness on one side of the body, sudden and severe

weight gain or loss

yellow eyes or skin

Incidence not known

Blistering, peeling, or loosening of the skin

cough

muscle pain

red irritated eyes

red skin lesions, often with a purple center

sores, ulcers, or white spots in the mouth or on the lips

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Difficulty having a bowel movement (stool)

difficulty with moving

increased or decreased appetite

swelling or redness in the joints

Less common

Acid or sour stomach

belching

blistering, crusting, irritation, or reddening of the skin

canker sores

discouragement

feeling sad or empty

flushing or redness of the skin

heartburn

indigestion

irritability

loss of interest or pleasure

redistribution or accumulation of body fat

skin rash, encrusted, scaly, and oozing

sores, ulcers, or white spots on the lips or tongue or inside the mouth

stomach discomfort or upset

tiredness

trouble in concentrating

unusually warm skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Maraviroc (Selzentry)

thumbs-up

Pros

Can be taken with or without food

Can be used in young children who weigh at least 4 pounds

Available in a liquid form for people who have difficulty swallowing pills

Tablets are available in many different strengths for dose adjustments

thumbs-down

Cons

Doesn't work for every type of HIV, requires a tropism test before starting treatment

Interacts with many medications, like efavirenz (Sustiva) and ritonavir (Norvir)

Not a good option for people with severe kidney problems

Must be taken twice a day with other HIV ARVs

pharmacist-tips

Pharmacist tips for Maraviroc (Selzentry)

pharmacist
  • Take maraviroc (Selzentry) every day, along with other HIV ARVs, to help the medication work the best it can. If you accidentally miss a dose, take it as soon as you remember. But don’t double up, as this can raise your risk of side effects.

    • You can take maraviroc (Selzentry) with or without food. It might be best to take your two doses 12 hours apart.

      • Get your routine blood tests done on time before and during treatment with maraviroc (Selzentry). This helps your healthcare team check that the medication is working for you and not causing side effects.

        • Speak with your HIV specialist before stopping maraviroc (Selzentry) or any of your HIV medications. Stopping your HIV medications too soon can cause the virus to spread and become harder to treat.

          • If your child is taking maraviroc (Selzentry) and you notice major weight changes, let their HIV specialist know. The dose of the medication might need to be adjusted based on your child’s weight.

            • Maraviroc (Selzentry) can interact with many other medications. This might mean some medications need to be stopped, or the dose of maraviroc (Selzentry) might need to be adjusted. Let your healthcare team know about all the medications you're taking, including over-the-counter products and supplements.

              • Maraviroc (Selzentry) can cause serious liver problems. Let your HIV specialist know if you experience symptoms such as itchy rash, yellowing of your skin or the whites of your eyes, vomiting, dark urine, or stomach pain.

                More tips for taking maraviroc (Selzentry) oral solution

                • Maraviroc (Selzentry) oral solution should be kept in its original container and at room temperature. Once the bottle has been opened, throw away any remaining liquid 60 days after.

                  • Maraviroc (Selzentry) oral solution will come with a press-in bottle adaptor and 2 oral syringes. Follow the directions included with the medication to make sure you or your child is getting the correct dose.

                    faqs

                    Frequently asked questions about Maraviroc (Selzentry)

                    Is maraviroc (Selzentry) safe?
                    It can be when taken as prescribed. A study showed that people taking maraviroc (Selzentry) kept benefiting from the treatment after two years, and the number of side effects was similar to those in people taking a placebo. Keep in mind that if you have a history of kidney, heart, or liver problems, talk to your healthcare team before starting this medication.
                    How effective is maraviroc (Selzentry)?
                    One study showed that 41% of people who took maraviroc (Selzentry) twice a day had undetectable viral loads 1 year after they started treatment. Within those 41% of people, 87% of people maintained undetectable viral loads 2 years after they started treatment. If you have any questions about whether maraviroc (Selzentry) is right for you, follow up with your HIV specialist for more information.
                    Does maraviroc (Selzentry) work for COVID-19?
                    Maraviroc (Selzentry) is currently only FDA-approved for treating CCR5-tropic HIV infection. But it's being studied in several clinical trials for treating long COVID-19 symptoms. The results haven't been published yet and more research is still needed.
                    Can you take maraviroc (Selzentry) with other HIV medications?
                    Yes. Maraviroc (Selzentry) must be taken along with other HIV ARVs for complete treatment of HIV. Keep in mind that some HIV ARV medications can interfere with how well your body clears maraviroc (Selzentry) from your system. This can affect the amount of maraviroc (Selzentry) in your body, how well it works, and the risk of side effects. Your HIV specialist will adjust your dose depending on the other medications you're taking.
                    When was maraviroc (Selzentry) FDA approved?
                    Maraviroc (Selzentry) was FDA approved in the United States to treat HIV in August 2007.
                    Does maraviroc (Selzentry) make you tired?
                    Although maraviroc (Selzentry) isn't known to cause tiredness, it can affect your ability to fall asleep as well as to stay asleep. Talk to your HIV specialist if you have trouble sleeping after starting treatment with this medication. If you have other symptoms, such as fever, cough, rash, or itching along with tiredness, let your care team know right away. These might be symptoms of more serious medical conditions, such as an infection or liver problems.
                    Should maraviroc (Selzentry) be taken with food?
                    Maraviroc (Selzentry) can be taken with or without food. But keep in mind that this medication must be taken with other ARVs for complete treatment of HIV. Some of the other HIV ARVs, such as ritonavir (Norvir) or efavirenz (Sustiva), might need to be taken with food or on an empty stomach to work well. As a result, check the instructions for all of your HIV ARVs before starting treatment. Talk to your HIV specialist if you're unsure about how to take your medications.
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                    What are the risks and warnings for Maraviroc (Selzentry)?

                    Maraviroc (Selzentry) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                    risk-warning

                    Liver problems

                    • Risk factors: Hepatitis B or C | History of liver problems

                      Maraviroc (Selzentry) can cause life-threatening liver problems. These are more common in the first month of treatment. Your HIV specialist will order blood tests for you before and during treatment so they can make sure this medication is safe for your liver. It's also known that allergic reactions, like severe rash and fever, often happen before any liver problems appear. Let your care team know immediately if you experience rash, hives, shortness of breath, feeling sleepy, nausea, loss of appetite, light-colored stool, upper right stomach pain, yellowing of the skin or eyes, or dark urine.

                      risk-warning

                      Severe skin reactions and allergic reactions

                      • Risk factor: Taking medications that can cause allergic reactions

                        Maraviroc (Selzentry) can sometimes cause rash and other severe skin reactions. In rare cases, these skin reactions can lead to hospitalization and other complications. The risk is higher if you're also taking medications that also have a higher risk of causing allergic reactions. Get medical care right away if you have a rash, blistering or peeling skin, painful sores on your face, swelling, or trouble breathing.

                        risk-warning

                        Heart problems and low blood pressure

                        • Risk factors: History of heart problems | History of kidney problems

                          In one study, some people who took maraviroc (Selzentry) had a heart attack during treatment. Although it's not clear how much this medication affects the heart, it's important to let your healthcare team know if you have a history of heart problems before starting maraviroc (Selzentry). Get medical attention right away if you have symptoms of a heart attack, such as chest pain, sweating, nausea, or dizziness.

                          In addition, maraviroc (Selzentry) can also cause low blood pressure when your body changes positions. This can make you feel dizzy and lightheaded when you stand up, and it can be worse for people with kidney problems. Talk to your HIV specialist if this happens to you, they might need to adjust your dose.

                          risk-warning

                          Overactive immune system

                          Taking HIV ARV therapy, such as maraviroc (Selzentry), can cause changes to your immune system called immune reconstitution syndrome. This condition happens when your immune system becomes overly active after you start combination therapy. So your immune system begins to fight off different infections that it was too weak to fight off before you started treatment. In rare cases, your immune response might improve too much with treatment that it starts to attack normal cells in your body (autoimmune). You can develop these conditions as early as during the first few weeks of treatment or many months later. Tell your healthcare team right away if you start having any new symptoms, such as fever, pain, hair loss, bulging eyes, or sweating, after starting maraviroc (Selzentry).

                          risk-warning

                          Serious infections

                          • Risk factors: Active, chronic (long-term), or recurrent infection | Taking other medications that can lower the immune system

                            Maraviroc (Selzentry) can lower your ability to fight infections. Serious infections, such as upper respiratory tract infection and herpes infection, have happened in people taking this medication. If you take certain medications, like corticosteroids, with maraviroc (Selzentry), you'll likely need to be careful since this raises your risk of getting a serious infection. Let your healthcare team know right away if you have signs or symptoms of an infection, such as fever, cough, or sore throat.

                            risk-warning

                            Interactions with other medications

                            Some medications can interfere with how well your body gets rid of maraviroc (Selzentry) from your system. This can affect the amount of maraviroc (Selzentry) in your body, how well it works, and the risk of side effects.

                            Taking tuberculosis medication (e.g., rifampin (Rifadin)) can lower the amount of maraviroc (Selzentry) in your body. This can make maraviroc (Selzentry) not work as well to treat your HIV. On the other hand, taking clarithromycin can raise the amount of maraviroc (Selzentry) in your body. This can lead to more side effects, such as upper respiratory tract infections.

                            Because maraviroc (Selzentry) can have serious interactions with other medications, tell your healthcare team about all the medications you take or plan to take. They’ll check that it's safe to use them together.

                            dosage

                            Maraviroc (Selzentry) dosage forms

                            The average cost for 60 tablets of 300mg of Maraviroc (Selzentry) is $396.41 with a free GoodRx coupon. This is 71.13% off the average retail price of $1373.28.
                            tablet
                            Tablet
                            DosageQuantityPrice as low asPrice per unit
                            150mg60 tablets$396.41$6.61
                            300mg60 tablets$396.41$6.61

                            Typical dosing for Maraviroc (Selzentry)

                            Maraviroc (Selzentry) is available as oral tablets and an oral solution (20 mg/mL). Your dose might be different depending on your kidney health and other medications you take.

                            • Adults: The typical dose ranges from 150 mg to 600 mg by mouth twice daily.

                            • Children: Dosage for children is dependent on their body weight.

                              • Weighing at least 88 pounds: The typical dose ranges from 150 mg to 300 mg by mouth twice daily.

                              • Weighing 66 to 87 pounds: The typical dose ranges from 100 mg to 300 mg by mouth twice daily.

                              • Weighing 44 to 65 pounds: The typical dose ranges from 75 mg to 200 mg by mouth twice daily.

                              • Weighing 31 to 43 pounds: The typical dose ranges from 50 mg to 200 mg by mouth twice daily.

                              • Weighing 22 to 30 pounds: The typical dose ranges from 50 mg to 150 mg by mouth twice daily.

                              • Weighing 13 to 21 pounds: The typical dose is 100 mg by mouth twice daily.

                              • Weighing 9 to 12 pounds: The typical dose is 40 mg by mouth twice daily.

                              • Weighing 4 to 8 pounds: The typical dose is 30 mg by mouth twice daily.

                            interactions

                            Interactions between Maraviroc (Selzentry) and other drugs

                            Maraviroc (Selzentry) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Maraviroc (Selzentry). Please note that only the generic name of each medication is listed below.

                            Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                            Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                            • Abametapir
                            • Cabotegravir
                            • Capmatinib
                            • Ceritinib
                            • Duvelisib
                            • Fosnetupitant
                            • Ivosidenib
                            • Larotrectinib
                            • Lasmiditan
                            • Lefamulin
                            • Lorlatinib
                            • Lumacaftor
                            • Netupitant
                            • Pexidartinib
                            • Venetoclax
                            drug-cost

                            How much does Maraviroc (Selzentry) cost?

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                            contraindications-icon

                            Maraviroc (Selzentry) contraindications

                            Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Maraviroc (Selzentry) will not be safe for you to take.
                            • People with severe kidney problems who are taking certain medications that interact with maraviroc (Selzentry) (e.g., clarithromycin, Triumeq)

                            alternatives

                            What are alternatives to Maraviroc (Selzentry)?

                            There are a number of medications that your doctor can prescribe in place of Maraviroc (Selzentry). Compare a few possible alternatives below.
                            Maraviroc (Selzentry)
                            Used for:
                            $396.41 Lowest GoodRx priceView Prices
                            Used for:
                            • Treatment of HIV infection in people ages 3 months and older

                            $42.58 Lowest GoodRx priceView Prices
                            Used for:
                            • Treatment of HIV infection

                            $66.08 Lowest GoodRx priceView Prices
                            images

                            Maraviroc (Selzentry) images

                            Blue Oval I3 And 25 - Maraviroc 300mg Tablet
                            This medicine is Blue, Oval Tablet Imprinted With "25" And "I3".Blue Oval I3 And 25 - Maraviroc 300mg Tablet

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                            References

                            Best studies we found

                            ClinicalInfoHIV.gov. (n.d.). CCR5.

                            ClinicalInfoHIV.gov. (n.d.). Immune reconstitution inflammatory syndrome (IRIS).

                            ClinicalInfoHIV.gov. (n.d.). R5-tropic virus.

                            View All References (7)

                            ClinicalInfoHIV.gov. (2018). Laboratory testing. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV.

                            ClinicalTrials.gov. (n.d.). Search results: Maraviroc. National Library of Medicine.

                            Hardy, W. D., et al. (2010). Two-year safety and virologic efficacy of maraviroc in treatment-experienced patients with CCR5-tropic HIV-1 infection: 96-week combined analysis of MOTIVATE 1 and 2. Journal of Acquired Immune Deficiency Syndromes.

                            HIVinfo.NIH.gov. (2021). Drug resistance.

                            Thapa, S., et al. (2023). Immune reconstitution inflammatory syndrome. StatPearls.

                            U.S. Food and Drug Administration. (2009). Selzntry (maraviroc) 150 mg, and 300 mg tablets.

                            ViiV Healthcare Company. (2022). Selzentry- maraviroc tablet, film coated; Selzentry- maraviroc solution; Selzentry- maraviroc [package insert]. DailyMed.

                            GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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