Lupaneta (leuprolide / norethindrone) is a treatment that helps relieve endometriosis-related pain. There are two parts to this combination therapy: leuprolide injections in the muscle and norethindrone acetate tablets taken by mouth. It's no longer available in the United States because it was discontinued.
Endometriosis
Lack of menstrual periods due to hormonal imbalance (secondary amenorrhea)
Abnormal vaginal bleeding due to hormonal imbalance
Endometriosis
Before fibroid surgery to help improve anemia due to bleeding from uterine fibroids
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AbbVie Inc. (2023). Lupaneta pack- leuprolide acetate and norethindrone acetate [package insert]. DailyMed.
Soliman, S. M., et al. (2016). Analysis of adherence, persistence, and surgery among endometriosis patients treated with leuprolide acetate plus norethindrone acetate add-back therapy. Journal of Managed Care & Specialty Pharmacy.
U.S. Food and Drug Administration. (n.d.). Drugs@FDA: FDA-approved drugs - Lupaneta pack.
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