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Liptruzet

ezetimibe and atorvastatin
Used for High Cholesterol

Liptruzet (ezetimibe / atorvastatin) is a combination medication used to treat high cholesterol and triglycerides (fats). This medication has been discontinued and is no longer available in the United States.

Reviewed by:Last reviewed on July 15, 2022
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What is Liptruzet (ezetimibe / atorvastatin)?

What is Liptruzet (ezetimibe / atorvastatin) used for?

  • High cholesterol
  • High triglycerides

Drug facts

Common BrandsLiptruzet(brand no longer available)
Drug ClassCholesterol absorption inhibitor / Statin
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
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Common questions about Liptruzet (ezetimibe / atorvastatin)

Liptruzet (ezetimibe / atorvastatin) is a combination of two medications, ezetimibe and atorvastatin. Ezetimibe works by reducing the amount of cholesterol that's absorbed by the body. Atorvastatin works by blocking your liver from making cholesterol. By working together, the two medications help lower low-density lipoprotein (LDL, or "bad" cholesterol) and triglycerides.

No, Liptruzet (ezetimibe / atorvastatin) has been discontinued and is no longer available in the United States.

Liptruzet (ezetimibe / atorvastatin) was voluntarily discontinued due to business reasons. The FDA determined that Liptruzet (ezetimibe / atorvastatin) wasn't discontinued due to safety concerns or because it didn't work well.

Both of the active ingredients in Liptruzet (ezetimibe / atorvastatin) are still available as single-ingredient medications: ezetimibe (Zetia) and atorvastatin (Lipitor). There's also a combination cholesterol medication currently on the market (ezetimibe / simvastatin (Vytorin)). This medication contains ezetimibe, which is also found in Liptruzet (ezetimibe / atorvastatin) and simvastatin. Simvastatin is similar to atorvastatin, which is the other active ingredient found in Liptruzet (ezetimibe / atorvastatin). There are many other medications available for lowering cholesterol and triglycerides. Talk to your provider about what the best treatment option might be for you.

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Liptruzet (ezetimibe / atorvastatin) dosage

Typical dosage for Liptruzet (ezetimibe / atorvastatin)

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Interactions between Liptruzet (ezetimibe / atorvastatin) and other drugs

Liptruzet (ezetimibe / atorvastatin) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Liptruzet (ezetimibe / atorvastatin). Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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What are alternatives to Liptruzet (ezetimibe / atorvastatin)?

There are a number of medications that your doctor can prescribe in place of Liptruzet (ezetimibe / atorvastatin). Compare a few possible alternatives below.
Liptruzet (ezetimibe / atorvastatin)
Used for:
  • High cholesterol
  • High triglycerides

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