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Levulan

Levulan Side Effects

Connie Zheng, PharmDKristianne Hannemann, PharmD
Reviewed by Connie Zheng, PharmD, Kristianne Hannemann, PharmD
Last reviewed on December 14, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Redness (up to 100%)
  • Stinging or burning (up to 96%)
  • Dryness, peeling, or crusting on the skin (64-87%)
  • Skin color changes (22-73%)
  • Swelling (up to 56%)
  • Fluid-filled blisters (up to 41%)
  • Itchy skin (14-25%)

Less Common Side Effects

  • Damaged skin
  • Welts
  • Bleeding
  • Scabbing
  • Tingling sensation

Source: DailyMed

The following Levulan side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bleeding

hives

persistent non-healing sore

pink growth

reddish patch or irritated area

scabbing

shiny bump

spots on your skin resembling a blister or pimple

stinging, burning, pain, redness, swelling, scaling, crusting, lightening or darkening of the skin, itching, cracking, crusting, or dryness of the skin at the application site

tenderness

white, yellow or waxy scar-like area

Less common

Bleeding during lesion preparation

blistering or irritation of the skin

flaking, pain, peeling, itching rash, breaking down of the skin

Incidence not known

Difficulty seeing at night

double vision

increased sensitivity of the eyes to sunlight

loss of memory

problems with memory

red, sore eyes

seeing double

swelling of the eyelids

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Burning, crawling, itching, numbness, prickling, “pins and needles,” stinging, or tingling feelings

darkening or lightening of the treated skin

skin sore

small, red, raised, itchy bumps

swelling of the skin

Less common

Cough

fever

headache

oozing

open sore on the skin

pain

pain or tenderness around the eyes and cheekbones

pus filled blister or pimple

raw skin

stuffy or runny nose

tenderness

tightness of the chest

troubled breathing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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