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Lartruvo
Lartruvo (olaratumab) is an injectable medication that's given together with doxorubicin (Adriamycin) for the treatment of soft tissue sarcoma (STS) in adults who can't get surgery or radiotherapy. This medication was taken off the market and is no longer available in the U.S.
Last reviewed on July 31, 2022
What is Lartruvo (olaratumab)?
What is Lartruvo (olaratumab) used for?
Soft tissue sarcoma (STS)
How Lartruvo (olaratumab) works
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Drug Facts
Common BrandsLartruvo (brand no longer available)
Drug ClassAnticancer
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Frequently asked questions about Lartruvo (olaratumab)
What is Lartruvo (olaratumab)?
Lartruvo (olaratumab) is an anticancer medication used to treat soft tissue sarcoma (STS) for people who can't get surgery or radiotherapy. This medication is given as an infusion into the vein and in combination with doxorubicin (Adriamycin) treatment. Lartruvo (olaratumab) works by attaching to a protein on the surface of cells that's responsible for growth and movement. Since this protein is also found on cancer cells (including those of STS), blocking the protein can help slow or stop the growth of the cancer. Lartruvo (olaratumab) was approved by the FDA in 2016 under their Accelerated Approval program based on early studies showing potential benefits of the medication to people with this rare cancer.
Is Lartruvo (olaratumab) still available?
No, Lartruvo (olaratumab) has been withdrawn from the market and is no longer available.
Why was Lartruvo (olaratumab) discontinued?
Lartruvo (olaratumab) was discontinued by the manufacturer (Eli Lilly and Co.), because there wasn't enough clinical evidence that the medication could improve survival for people with STS. Because of this, the FDA decided to withdraw Lartruvo (olaratumab) from the market. Speak with your provider about other treatment options for your particular STS.
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