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Jetrea

ocriplasmin
Used for Vitreomacular Adhesion
Used for Vitreomacular Adhesion

Ocriplasmin is a medication used to treat an eye condition called symptomatic vitreomacular adhesion. It only requires one dose and is given as an injection into the eye by a healthcare provider. This medication has been discontinued, so it's no longer available in the United States.

Reviewed by:
reviewer
Yen Nguyen, PharmD
reviewer
Cydnee Ng, PharmD
Last reviewed on May 4, 2022
BasicsFAQsInteractionsPricesMedicare
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What is Ocriplasmin?

How Ocriplasmin works

Drug Facts

Common BrandsJetrea (brand no longer available)
Drug ClassEnzyme
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Ocriplasmin

What is ocriplasmin?
Ocriplasmin is a medication injected into the eye to treat symptomatic vitreomacular adhesion. This is an eye condition where the vitreous (jelly part of the eye) attaches to the macula (central part of the eye) and pulls on it. This can negatively affect your vision and can potentially lead to vision loss. Ocriplasmin is an enzyme that works by dissolving the proteins that cause the attachment between the vitreous and macula.
Is ocriplasmin still available?
No, ocriplasmin was discontinued by the manufacturer.
Why was ocriplasmin discontinued?
Ocriplasmin was discontinued due to business reasons in May 2020.
Are there any alternatives to ocriplasmin?
Ocriplasmin was one of the few nonsurgical options for symptomatic vitreomacular adhesion. Besides close monitoring by your provider, an alternative to ocriplasmin is eye surgery (vitrectomy). Ask your provider about other options and their risks and benefits.
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interactions

Interactions between Ocriplasmin and other drugs

Ocriplasmin may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Ocriplasmin. Please note that only the generic name of each medication is listed below.

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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