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hydrocortisone / iodoquinol

Generic Vytone
Used for Skin Infection, Eczema, Itching, Athlete's Foot, Ringworm, Jock Itch
Used for Skin Infection, Eczema, Itching, Athlete's Foot, Ringworm, Jock Itch

Vytone (hydrocortisone / iodoquinol) is a combination medication that is used to treat various skin infections and inflammatory conditions of the skin. It needs to be applied multiple times per day and it can be expensive.

Reviewed by:
reviewer
ThienLy Neal, PharmD
reviewer
Allison Gourley, PharmD
Last reviewed on October 7, 2021
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostImagesPricesMedicare
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What is Vytone (hydrocortisone / iodoquinol)?

What is Vytone (hydrocortisone / iodoquinol) used for?

  • Skin infections

  • Inflammatory conditions of the skin

How Vytone (hydrocortisone / iodoquinol) works

Vytone (hydrocortisone / iodoquinol) is a combination of an anti-infective medication, iodoquinol, and a corticosteroid, hydrocortisone. It's uncertain how iodoquinol works, but it's both an antifungal and antibacterial which helps to treat various types of infection. Hydrocortisone stops chemicals in the body that cause swelling, inflammation, and itching.

Drug Facts

Common BrandsVytone
Drug ClassCorticosteroid / Anti-infective
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityNot FDA-approved yet
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Avg retail price
$662.260
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$662.26
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What are the side effects of Vytone (hydrocortisone / iodoquinol)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Burning sensation on skin
  • Itchy skin
  • Irritated skin
  • Dry skin

Other Side Effects

  • Inflamed hair follicles
  • Excessive hair growth on the body
  • Acne
  • Discoloration of skin
  • Inflamed skin around the mouth area

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Allergic reactions

Source: DailyMed

The following side effects have also been reported

Side effects that you should report to your care team as soon as possible:

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Change in skin color
  • Fragile or thinning skin that bruises easily
  • Mild skin irritation, redness, or dryness
  • Small, red, pus-filled bumps on skin around hair follicles
  • Unexpected hair growth at application site
pros-and-cons

Pros and cons of Vytone (hydrocortisone / iodoquinol)

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Pros

Combination of two medications that help to treat skin conditions in different ways

Can be used in children as young as age 12

Can be used to treat many different types of skin problems

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Cons

Can be expensive, even as a generic

Has to be applied multiple times a day

Long-term use isn't recommended.

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Pharmacist tips for Vytone (hydrocortisone / iodoquinol)

pharmacist

  • Wash your hands before and after using Vytone (hydrocortisone / iodoquinol). Don't put Vytone (hydrocortisone / iodoquinol) on any damaged skin or open wounds.

    • Don't use Vytone (hydrocortisone / iodoquinol) longer than what your provider has told you to do. Long-term use of this medication can cause an overgrowth of other bacteria that aren't killed by Vytone (hydrocortisone / iodoquinol).

      • Make sure to not cover the medicated area with a bandage or dressing, because more Vytone (hydrocortisone / iodoquinol) can be absorbed into the body and can raise your risk of side effects.

        • Vytone (hydrocortisone / iodoquinol) can stain your clothes, fabrics, skin, and hair. Be careful to only apply this medication to the affected area(s).

          • Before applying this medication, make sure the affected area has been properly cleaned and dried so that enough medication can be absorbed.

            • If you develop irritation to Vytone (hydrocortisone / iodoquinol) at any point during treatment, stop using it. Let your provider know right away. You will need to be switched to a different medication.

              faqs

              Frequently asked questions about Vytone (hydrocortisone / iodoquinol)

              How long should I use Vytone (hydrocortisone / iodoquinol) for?
              How long you use Vytone (hydrocortisone / iodoquinol) will depend on the type of skin condition that's being treated. Only use Vytone (hydrocortisone / iodoquinol) for the amount of time your provider says. Long-term use of this medication can cause overgrowth of other bacteria that aren't killed by Vytone (hydrocortisone / iodoquinol) which can lead to other types of infections.
              Can I use Vytone (hydrocortisone / iodoquinol) with other topical steroid medications?
              One component of Vytone (hydrocortisone / iodoquinol), hydrocortisone, belongs to the steroid drug class which helps to reduce inflammation, itching, and swelling of the skin. Hydrocortisone topicals alone are commonly available over-the-counter (OTC), so it's important to not use these in addition to Vytone (hydrocortisone / iodoquinol), because you may get too much corticosteroid in your system.
              Can Vytone (hydrocortisone / iodoquinol) cause burning?
              A burning sensation on the skin is a possible side effect of this medication. This is due to the hydrocortisone component of Vytone (hydrocortisone / iodoquinol). If your skin becomes too irritated, let your provider know. You may need to switch to a different medication.
              Can I use Vytone (hydrocortisone / iodoquinol) on my face?
              You can use Vytone (hydrocortisone / iodoquinol) on your face, however be very careful not to get any of the medication in your eyes, nose, or mouth.
              How much Vytone (hydrocortisone / iodoquinol) should I apply each time?
              Put a thin layer of Vytone (hydrocortisone / iodoquinol) over the affected area and rub it in gently. Don't use coverings like bandages or dressings over the area unless your provider tells you to.
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              What are the risks and warnings for Vytone (hydrocortisone / iodoquinol)?

              Vytone (hydrocortisone / iodoquinol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Keep in a safe place

              Make sure to keep Vytone (hydrocortisone / iodoquinol) in a safe place out of the reach of children and pets. It can be very harmful if not handled or used properly.

              risk-warning

              External use only

              Vytone (hydrocortisone / iodoquinol) is meant for external use (on the outside of the body) only. Don't get this medication in your eyes, nose, mouth, or vagina. If there's contact to these areas, make sure to rinse the area with water really well.

              risk-warning

              Pregnancy

              It's unknown if Vytone (hydrocortisone / iodoquinol) can cause harm to an unborn baby or if it's safe to use in pregnant women. Vytone (hydrocortisone / iodoquinol) should only be used if absolutely needed and your provider has determined that the benefits are greater than the risks to you and your unborn baby.

              dosage

              Vytone (hydrocortisone / iodoquinol) dosage forms

              The average cost for 1 carton of 30 packets of 1.9%/1% of Vytone (hydrocortisone / iodoquinol) is $865.34 with a free GoodRx coupon. This is 14.92% off the average retail price of $1017.06.
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              DosageQuantityPrice as low asPrice per unit
              30 packets of 1.9%/1%1 carton$865.34$865.34

              Typical dosing for Vytone (hydrocortisone / iodoquinol)

              Apply to the affected area(s) 3 to 4 times daily or as instructed by your provider.

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              Vytone (brand)
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              Vytone (hydrocortisone / iodoquinol) (generic)
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              $662.26

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