Why was Hycofenix discontinued?

It's not clear why Hycofenix was taken [off the market](https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=BasicSearch.process).

Hycofenix

hydrocodone / pseudoephedrine / guaifenesin

Used for Cold Symptoms, Cough, Nasal Congestion

Hycofenix is a combination medication containing hydrocodone, pseudoephedrine, and guaifenesin. It's used to relieve symptoms of cough, stuffy nose, and mucus from the common cold in people 18 years and older. Hycofenix is a liquid that's easy to take, but it's no longer available in the United States.

Reviewed by:

Yen Nguyen, PharmD

Kristianne Hannemann, PharmD

Last reviewed on January 11, 2022

Hycofenix is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.

What is Hycofenix?

Drug facts

Common Brands	Hycofenix(brand no longer available)
Drug Class	Opioid / Alpha agonist / Expectorant
Controlled Substance Classification	Schedule II
Generic Status	No lower-cost generic available
Availability	Discontinued

Common Brands

Hycofenix(brand no longer available)

Drug Class

Opioid / Alpha agonist / Expectorant

Controlled Substance Classification

Schedule II

Generic Status

No lower-cost generic available

Availability

Discontinued

Common questions about Hycofenix

Hycofenix is a combination of three medications that work together to relieve symptoms of a common cold. Hydrocodone is an opioid that helps relieve pain and control cough. Pseudoephedrine is an alpha agonist that works as a decongestant to clear your sinuses and airways to make it easier to breathe. Guaifenesin is an expectorant that thins and loosens the mucus in your lungs to make it easier to cough up.

No, Hycofenix is no longer available in the United States.

It's not clear why Hycofenix was taken off the market.

If you used Hycofenix in the past or you currently have cold symptoms, discuss other options with your healthcare provider. Depending on the nature of your condition and your medical history, your provider will help guide you to a medication that's best for you.

Hycofenix

Hycofenix is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.

What is Hycofenix?

Drug facts

Common questions about Hycofenix

Hycofenix dosage

Typical dosage for Hycofenix

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Common questions about Hycofenix

Hycofenix is a controlled substance, which means that it's more likely to be misused or cause dependence. There are federal and state laws that limit the amount of medication that can be prescribed or dispensed within a certain period of time.

What is Hycofenix?

Drug facts

Common questions about Hycofenix

What is Hycofenix?

Is Hycofenix still available?

Why was Hycofenix discontinued?

What can I take to replace Hycofenix?

Hycofenix dosage

Typical dosage for Hycofenix

Common questions about Hycofenix

What is Hycofenix?

Is Hycofenix still available?

Why was Hycofenix discontinued?

What can I take to replace Hycofenix?