Key takeaways:
About 7 million people in the United States donate blood each year. But nearly 20% of donors are turned away for different reasons, such as low hemoglobin due to low iron levels.
Some people may be able to boost iron levels before donating blood. Eating iron-rich foods or taking iron supplements can help raise your iron levels.
Talk with your medical provider if you have low hemoglobin or iron levels. This can be a sign of an underlying medical condition.
Close to 7 million people in the United States donate at least one unit of blood every year. And about 20% are turned away for various reasons.
In order to donate blood, potential donors have to meet certain requirements. One of the most likely reasons for being turned down as a blood donor is a low hemoglobin — commonly due to a low iron level.
This can come as a surprise, especially if you’ve been donating for years. But iron deficiency, with or without anemia, can happen for many reasons and you may not have any symptoms. Iron deficiency can be a sign of an underlying medical condition. And donating blood can cause iron deficiency or worsen it if you donate often. Let’s take a closer look at why your iron level is important when donating blood and how you can safely raise your iron levels.
Iron is an essential mineral found in nature. Your body can’t make its own iron. People get it by eating foods rich in iron.
Hemoglobin is a protein. If your body has enough iron and amino acids (protein building blocks), it can make all the hemoglobin it needs.
Iron and hemoglobin are assembled together and packed into red blood cells. Together they carry oxygen and deliver it to all the tissues in the body.
Blood banks don’t actually measure the iron level at the time of donation. Instead they look at hemoglobin level. Hemoglobin is easy to measure, and in some cases it can help to give a good estimate of whether you have enough iron.
The requirements for hemoglobin for blood donors are:
Male donors: more than 13 mg/dL
Female donors: more than 12.5 mg/dL
Maximum hemoglobin: 20 mg/dL
If your hemoglobin is lower than the minimum level, you’ll be able to try again in a few weeks.
The most common ways to raise your iron is through the food you eat, iron supplements, and improving how much iron your body absorbs.
Most people get enough iron from the food they eat. But if you’re looking for a boost in your iron before donating blood, focusing on iron-rich foods may help.
Iron in food may be bound to a protein called heme (one of the building blocks of red blood cells). This type of iron is easily absorbed, but only makes up about 10% of iron in the diet. Iron may also be unbound (nonheme). This type of iron isn’t as easily absorbed and makes up most of the iron we get from the diet.
Some of the foods that are high in iron include:
Meats, shellfish (especially oysters), poultry, organ meats
Fortified grains and cereals
Green leafy vegetables
Beans and legumes
Sesame seeds and cashews
Many regular blood donors can’t restore their iron levels by just eating iron-rich foods. But you may benefit from taking iron supplements. Iron can be found in many multivitamins. Or it can be taken as a separate supplement.
Either way, you’ll want to aim for the recommended daily dose for you. This will usually be based on your age and if you have a monthly menstrual cycle. It's important to take the proper dose so you don’t take too much or too little iron.
Increasing how much iron you’re absorbing through your diet can give you a boost before donating blood. One way to improve how much iron is absorbed through your gut is to consume vitamin C at the same time. Foods that have lots of vitamin C and can increase your iron absorption are:
Citrus
Strawberries
Tomatoes
Sweet peppers
You can also take a vitamin C supplement with your food or an iron pill to help you absorb more.
If your iron level is on the lower end of normal, you may want to try to raise it before donating. Keep in mind that the change isn’t immediate. It may take at least a couple of weeks to see a difference in your blood levels. If your iron level doesn’t improve, your healthcare provider will want to do tests to find out why.
Certain foods, beverages, and medications can decrease how much iron you absorb from your food. You may want to avoid using these items for a short while when you’re preparing to donate blood, or taking iron supplements. Things that may decrease iron absorption include:
Coffee
Tea
Red wine
Chocolate
Foods high in fiber like soybean, black beans, and lentils
Antacids like calcium carbonate
Foods high in calcium like milk, cheese, and yogurt
If you’re taking an iron supplement, you should consider taking it at a different time than when you’re eating and drinking these items.
A low level of iron means your body can’t make enough red blood cells (anemia) to meet your body’s need for oxygen. Donating blood removes even more blood cells and causes your iron levels to drop even lower.
About 500 mL of blood is taken from your body when you donate blood. This is about 10% of the total amount of blood you have in your body. If you have a normal iron level when you donate, your body will be able to absorb more iron to replace what you lost. But if you’re already low, it will put extra strain on your body, making it more difficult to recover quickly.
Red blood cells carry oxygen to all parts of the body. Major organs like the brain, kidneys, and heart suffer when they don’t get enough oxygen.
People rely on donated blood every day. And millions of donors meet that need each year. But potential donors are turned away if they have low hemoglobin from low iron levels. Easy ways to boost your iron level before donating blood is to increase the amount of iron-rich foods you eat or take a supplement that contains iron. If you have a low iron or hemoglobin level that doesn’t respond to increased iron intake, talk with your healthcare provider.
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Association for the Advancement of Blood & Biotherapies. Hemoglobin screening/iron management.
Dietary Guidelines for Americans. (n.d.). Food sources of iron.
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National Institutes of Health, Office of Dietary Supplements. (2023). Iron: Fact sheet for health professionals.
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