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guanethidine
Guanethidine is a medication used for treating high blood pressure. It's no longer available in the United States because it was discontinued.
Last reviewed on June 29, 2022
What is Guanethidine?
What is Guanethidine used for?
High blood pressure
How Guanethidine works
Are you looking for information on guanfacine or guaifenesin (Mucinex) instead?
Drug Facts
Common BrandsIsmelin (brand no longer available)
Drug ClassAdrenergic blocker
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
Frequently asked questions about Guanethidine
What is guanethidine?
Guanethidine is an adrenergic blocker that's used to treat high blood pressure. It works by preventing the release of certain chemicals that constrict (tighten) your blood vessels. This causes your blood vessels to open up, which lowers your blood pressure.
Is guanethidine still available?
No, guanethidine has been discontinued and is no longer available in the United States. It's not clear why the medication was discontinued, but it's probably because newer medications are available.
Are there currently available medications that are used in place of guanethidine?
Yes, there are several available medications used to treat high blood pressure that are commonly used today. Examples include ACE inhibitors (e.g., lisinopril (Zestril)) and beta blockers (e.g., metoprolol (Lopressor)).
How to save using GoodRx
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What are alternatives to Guanethidine?
There are a number of medications that your doctor can prescribe in place of Guanethidine. Compare a few possible alternatives below.
Used for:
High blood pressure
Heart failure
Lower the risk for death after a heart attack
Used for:
Chest pain (angina)
Lower risk of death after heart attack
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