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Gonal F RFF

Gonal-F RFF Side Effects

Allison Gourley, PharmDKristianne Hannemann, PharmD
Reviewed by Allison Gourley, PharmD, Kristianne Hannemann, PharmD
Last reviewed on August 16, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Females:

Males

  • Acne (27%)
  • Injection-site pain (11%)
  • Tiredness (10%)

Less Common Side Effects

Females:

  • Bleeding between menstrual periods
  • Pain

Males

  • Oily, flakey skin
  • Growth of breast tissue
  • Lower sex drive

Gonal-F RFF serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reactions: trouble breathing, facial swelling, itchy skin, rash
  • Ovarian hyperstimulation syndrome: severe pelvic or stomach pain and swelling along with nausea, vomiting, sudden weight gain, diarrhea, trouble breathing, trouble urinating
  • Lung problems: trouble breathing, fluid in the lungs, worsening of any current lung problems
  • Heart attack: chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
  • Stroke: sudden trouble talking, trouble walking, numbness on one side of your body or face
  • Ectopic pregnancy: severe, unexplainable pelvic pain along with unusual vaginal bleeding
When do Gonal-F RFF possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Ovarian hyperstimulation syndrome
Seek immediate medical care if you experience this side effect.

Source: DailyMed

The following Gonal-F RFF side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Acid or sour stomach

anxiety

backache

belching

bloating

chest pain or tightness

confusion

cough

diarrhea

difficulty breathing

difficulty in speaking

dizziness or lightheadedness

double vision

excess air or gas in the stomach or intestines

fainting

fast heartbeat

fast, weak pulse

full feeling

headache

heartburn

inability to move the arms, legs, or facial muscles

indigestion

loss of appetite

noisy breathing

passing gas

pelvic pain, discomfort, aching, or heaviness

rapid weight gain

severe nausea

slow speech

stomach discomfort, upset, or pain, or swelling

sudden increase in stomach or shoulder pain

sweating

trouble breathing

unusual or large amount of vaginal bleeding

uterine bleeding between menstrual periods

vomiting

Incidence not known

Difficulty swallowing

dizziness

hives, itching, skin rash

pain the chest, groin, or legs, especially the calves

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

slurred speech

sudden loss of coordination

sudden, severe weakness or numbness in the arm or leg

unusual tiredness or weakness

vision changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acne

bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

dandruff

oily skin

swelling of the breasts or breast soreness in both females and males

Less common

Decreased interest in sexual intercourse

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.
Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

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