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Specialty Drug
ENFUVIRTIDE is an antiretroviral drug. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others. Compare HIV entry inhibitors.
Prescription Settings
60 vials of 90mg
1 kit
60 vials of 90mg
1 kit

Fuzeon Side Effects

What should I watch for?

Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.

HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.

This medicine causes injection site reactions. The reactions are usually mild to moderate, but can be severe. They usually happen within the first week of using the medicine and happen again as you keep using it. Each injection site reaction usually does not last longer than 7 days. The reactions may be worse when injections are given in the same place on the body or when the injection is given deeper than it should be (for example, into the muscle). Sometimes an injection site can get infected. Be sure to follow the instructions you get with this medicine. Following the instructions may help to lower your chance of getting an infection.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common


burning, numbness, tingling, or painful sensations or weakness in arms, hands, legs, or feet



pain or tenderness around eyes and cheekbones

shortness of breath or troubled breathing

stuffy or runny nose

tightness of chest



Less common




darkened urine

dry or itching eyes

excessive tearing

eye discharge

fast heartbeat



itching, pain, redness, swelling, tenderness, or warmth on skin at injection site

loss of appetite

lump or growth on skin


pains in stomach, side, or abdomen, possibly radiating to the back

redness, pain, swelling of eye, eyelid, or inner lining of eyelid


yellow eyes or skin


Difficulty in breathing or swallowing

fast heartbeat

skin itching, rash, or redness

swelling of face, throat, or tongue

Incidence not known

Black, tarry stools

bleeding gums

blood in urine or stools

bloody urine

chest pain

decreased frequency or amount of urine

inability to move arms and legs

increased blood pressure

increased thirst

lower back or side pain

painful or difficult urination

pale skin

pinpoint red spots on skin


sore throat

sudden numbness and weakness in the arms and legs

swelling of face, fingers, lower legs; weight gain

ulcers, sores, or white spots in mouth

unusual bleeding or bruising

unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Abnormal growth filled with fluid or semisolid material


burning or stinging of skin

decreased appetite



dry mouth


feeling sad or empty


hard lump


itching skin

lack of appetite

lack or loss of strength

large, flat, blue or purplish patches in the skin

muscle pain


painful cold sores or blisters on lips, nose, eyes, or genitals

redness of skin

small lumps under the skin


trouble concentrating

trouble sleeping

unusually warm skin

weight loss

Less common

Bad, unusual, or unpleasant (after) taste

burning, itching, and pain in hairy areas

change in taste


general feeling of discomfort or illness

joint pain

pus at root of hair

stomach pain

swollen, painful, or tender lymph glands in neck, armpit, or groin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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