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Flecainide

Flecainide Side Effects

Robert Chad Hakim, PharmD, BCCCPDaisy Chau, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Daisy Chau, PharmD
Last reviewed on November 18, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Dizziness (19%)
  • Vision changes (16%)
  • Shortness of breath (10%)
  • Headache (10%)
  • Nausea (9%)
  • Tiredness (8%)
  • Heart pounding (6%)
  • Chest pain (5%)
  • Weakness (5%)
  • Tremor (5%)
  • Constipation (4%)
  • Swelling in the arms and legs (4%)
  • Stomach pain (3%)

Less Common Side Effects

  • Vomiting
  • Diarrhea
  • Poor appetite
  • Fever
  • Rash
  • Double vision
  • Tingling or numbness
  • Sweating
  • Fainting
  • Sleepiness
  • Ringing in the ears
  • Anxiety
  • Trouble sleeping

Flecainide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Abnormal heart rhythm: chest pain, chest discomfort, palpitations, shortness of breath, fatigue, weakness, sweating
  • Heart failure: shortness of breath, swelling, sudden weight gain, coughing or wheezing, fast heart rate
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When do Flecainide possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Dizziness
Vision changes
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.

Source: DailyMed

The following Flecainide side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Difficult or labored breathing

dizziness, fainting, or lightheadedness

fast, irregular, pounding, or racing heartbeat or pulse

shortness of breath

tightness in the chest

wheezing

Less common

Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain

fainting

feeling of warmth

fever

increased sweating

partial or slight paralysis

redness of the face, neck, arms, and occasionally, upper chest

shakiness and unsteady walk

shakiness in the legs, arms, hands, or feet

swelling of the feet or lower legs

trembling or shaking of the hands or feet

unsteadiness, trembling, or other problems with muscle control or coordination

Rare

Arm, back, or jaw pain

black, tarry stools

bleeding gums

blood in the urine or stools

blurred vision

chest discomfort

chest tightness or heaviness

chills

confusion

convulsions

cough

decrease in the frequency of urination

decrease in urine volume

difficulty in passing urine (dribbling)

difficulty with breathing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

frequent urination

general feeling of discomfort or illness

headache

increased volume of pale, dilute urine

nausea

nervousness

noisy breathing

painful or difficult urination

pinpoint red spots on the skin

pounding in the ears

sensation of pins and needles

slow or fast heartbeat

sore throat

sores, ulcers, or white spots on the lips or in the mouth

stabbing pain

sweating

swollen glands

thickening of bronchial secretions

troubled breathing

unusual bleeding or bruising

unusual tiredness or weakness

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Blurred vision or seeing spots

Less common

Abdominal or stomach pain

acid or sour stomach

anxiety or mental depression

belching

constipation

continuing ringing or buzzing or other unexplained noise in the ears

depression

diarrhea

feeling of constant movement of self or surroundings

general feeling of discomfort or illness

hearing loss

heartburn

indigestion

lack or loss of strength

loss of appetite

sensation of spinning

sleepiness or unusual drowsiness

sleeplessness

skin rash

stomach discomfort, upset, or pain

trouble with sleeping

unable to sleep

weight loss

Rare

Bloated

change in color vision

change in taste

cracks in the skin

decreased awareness or responsiveness

decreased interest in sexual intercourse

difficulty seeing at night

difficulty with moving

dry mouth

excess air or gas in the stomach or intestines

eye pain or irritation

false or unusual sense of well-being

feeling of unreality

full feeling

hair loss or thinning of the hair

hives or welts

inability to have or keep an erection

increased sensitivity of the eyes to sunlight

itching skin

joint pain

lack of feeling or emotion

loss in sexual ability, desire, drive, or performance

loss of heat from the body

loss of memory

muscle aching or cramping

muscle pain or stiffness

passing gas

problems with memory

red, swollen skin

scaly skin

sense of detachment from self or body

severe sleepiness

swollen joints

swollen lips, mouth, or tongue

uncaring uncontrolled eye movements

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Daisy Chau, PharmD
Reviewed by:
Daisy Chau, PharmD
Daisy Chau, PharmD, is the drug information pharmacist manager at GoodRx. She is licensed in California and has more than 6 years of experience working as a pharmacist in drug information.

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