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Eversense

Used for Diabetes Type 2, Diabetes Type 1
Used for Diabetes Type 2, Diabetes Type 1

Eversense is a continuous glucose monitoring (CGM) system that gives you real-time glucose readings. The system contains a small sensor that's implanted under the skin in your upper arm by a healthcare provider every 6 months. It also comes with a transmitter that's placed right above the sensor, which sends information about your glucose levels to an app on your phone. Currently, Eversense is only FDA-cleared for use in adults 18 years and older with diabetes.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Allison Gourley, PharmD
Last reviewed on November 1, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageCostContraindicationsAlternativesLatest newsReferencesPricesMedicare
basics-icon

What is Eversense?

What is Eversense used for?

  • Monitor glucose levels

How Eversense works

The Eversense system is made up of 3 parts that work together to measure and record your glucose levels throughout the day.

  • Sensor: The sensor is inserted under the skin and measures your glucose levels from just underneath the skin.

  • Smart Transmitter: The rechargeable transmitter is worn over the sensor and connects to it. It sends the glucose readings via Bluetooth directly to the Eversense mobile app.

  • Eversense App: The app displays and stores your glucose readings.

Drug Facts

Common BrandsEversense
Drug ClassContinuous glucose monitoring
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only

More on Eversense essentials

Health: Diabetes: closeup woman checking blood sugar 1268676454

Dexcom vs. Eversense: 6 Differences Between These 2 Continuous Glucose Monitors

Written by Christina Aungst, PharmD
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What are the side effects of Eversense?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Skin irritation (6%)
  • Bruising (6%)
  • Pain (3%)
  • Thinning of the skin (2%)
  • Skin color change (2%)
  • Bleeding (2%)

Other Side Effects

  • Infection
  • Arm numbness
  • Tremor

Source: Prescribing Information

pros-and-cons

Pros and cons of Eversense

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Pros

Provides glucose readings for 6 months

Sensor can't get knocked off since it's implanted under the skin

Smart Transmitter alerts you to high or low glucose readings with a physical vibration

Sends real-time glucose data to an app on your phone

Allows you to share glucose data with your healthcare provider

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Cons

Must be implanted by a healthcare professional

Can't provide glucose readings during the 24-hour warm-up period

Needs to be used with an app on a smart device

Requires regular fingerstick calibrations

Must wear the Smart Transmitter over the sensor to get alerts about your glucose levels

pharmacist-tips

Pharmacist tips for Eversense

pharmacist

How to set up your Eversense:

  • After your provider implants the Eversense sensor, link the Smart Transmitter by turning it on and placing it over your bandage. Download the Eversense app and follow the instructions on it to complete the linking process. Watch this instructional video to learn more.

    • During the first 24 hours, Eversense will complete a warm-up period and won't provide glucose readings. You don't need to wear your Smart Transmitter during this time.

      How to start using your Eversense:

      • On day 2 after your procedure, use an adhesive patch to attach the Smart Transmitter directly over the sensor. Use a new adhesive to attach the Smart Transmitter each day going forward. You'll need to complete four fingerstick calibrations, with 2 hours between each one.

        • On day 3 after your procedure, the Eversense app will prompt you to complete two daily fingerstick calibrations. After a few weeks, you'll only need to complete one per day.

          • To check your glucose reading, go to the Eversense app on your mobile device.

            How to remove Eversense sensor:

            • The Eversense should be removed after 6 months by a healthcare provider. Contact your provider to schedule an appointment to have it removed.

              faqs

              Frequently asked questions about Eversense

              How is Eversense inserted?
              Eversense is inserted under the skin in your upper arm by a healthcare provider. You'll be awake during the procedure, and it should only take about 15 minutes. Your provider will first disinfect the area. Then, they'll put on some numbing medication and make a small cut (less than 1 cm) in order to place the sensor under your skin.
              Is the Eversense Smart Transmitter waterproof?
              The Eversense Smart Transmitter is water-resistant to up to about 3 feet of water for 30 minutes. It's not recommended to expose the transmitter to water for longer than this time, because doing so could damage it. You can take a quick shower with it for less than 30 minutes, but to be extra safe, you could remove the transmitter and put it back on with a new adhesive after your shower.
              How long does the Eversense Smart Transmitter last?
              The Smart Transmitter contains a rechargeable battery and it lasts for up to 1 year. After this time, it might not work properly to read your glucose level. Once you've had your Smart Transmitter for 1 year, talk to your healthcare provider about getting a new one.
              How often should I change the adhesive patch that attaches to the Eversense smart transmitter?
              You should change the adhesive that attaches to the Eversense smart transmitter once every 24 hours. If you notice red or irritated skin where you place the adhesive, let your provider know.
              How accurate is Eversense?
              Pretty accurate. Eversense has an overall mean absolute relative difference (MARD) of about 9%. The MARD shows how close its readings are to the actual glucose level in the blood. The smaller the MARD, the more accurate the CGM. Based on industry standards, a CGM with a MARD less than 10% is considered to be quite accurate and reliable.
              Can Eversense be used in children?
              No. Currently, Eversense is only FDA-cleared for use in adults 18 years and older. Talk to your child's provider about alternative CGM options.
              How often do I need to calibrate Eversense?
              You don't need to calibrate Eversense during the first 24 hours of having it placed in your arm. But you'll have to do regular calibrations using fingerstick readings from a blood glucose meter after that time. You'll need to complete the calibrations to make sure the sensor is providing accurate readings. At first you'll need to complete fingerstick calibrations multiple times a day, but after a few weeks you'll only need to do this once every 24 hours or as prompted.
              When do I need to have Eversense removed?
              Eversense must be removed after 180 days (or 6 months). At this time, it will stop sending glucose readings. If you want to continue using Eversense, contact your provider to remove your sensor and have a new one placed.
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              What are the risks and warnings for Eversense?

              Eversense can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

              risk-warning

              Low or high glucose levels

              • Risk factors: Injecting insulin near sensor

                If you have symptoms of low or high blood sugar and they aren't matching up with your Eversense readings, always do a fingerstick blood sugar test and contact your provider. Make sure to have a separate blood glucose monitor at home, since the app doesn't provide one. If you're taking insulin, don't inject it or insert an insulin pump within 4 inches of the sensor. This could lead to inaccurate glucose readings.

                risk-warning

                Infection at the incision site

                Make sure to keep the bandage on the incision where Eversense was placed in your arm for 48 hours. This will allow the site to heal and prevent infection. Also, don't swim or soak in a tub for 5 days. You should avoid strenuous activities until the site heals. While it's healing, always place a sterile bandage over the site before placing the Smart Transmitter on top of the sensor. If you notice redness, pain, swelling, or pus near the incision site later than 5 days after getting the sensor inserted, call your healthcare provider.

                risk-warning

                Electrical shock

                Don't use the Eversense Smart Transmitter if it's cracked or damaged, since this could raise the risk for electrical shock. In addition, the Smart Transmitter might not work properly anymore. Contact your provider to get a new Smart Transmitter if needed.

                risk-warning

                Electromagnetic interference

                Many sources of electromagnetic interference (EMI) can prevent the Eversense Smart Transmitter from sending glucose data to your mobile device. If this happens, move away from the source of EMI.

                risk-warning

                Risk of medications causing false glucose readings

                Certain medications can affect the accuracy of the glucose readings from Eversense. If you're taking a tetracycline antibiotic, your glucose readings might be falsely low. Don't rely on readings from Eversense while taking a tetracycline antibiotic. Instead, use your blood glucose meter to check your glucose level.

                risk-warning

                Damage to the sensor from medical procedures

                You should avoid getting certain procedures like lithotripsy, electrocautery, and diathermy treatment. These procedures can permanently damage the Eversense sensor. Additionally, you should avoid getting a massage in the area where the sensor was placed.

                risk-warning

                Interference from X-rays or CT scan

                Don't wear the Eversense Smart Transmitter during X-rays or CT scans, because this could interfere with glucose results. Make sure to let your provider know about your Smart Transmitter before getting an imaging procedure done.

                risk-warning

                Sensor not working properly

                If the Eversense sensor or Smart Transmitter feels warm, remove the Smart Transmitter and contact your provider. A warm sensor could mean it isn't working properly.

                dosage

                Eversense dosage forms

                The average cost for 1 meter of smart transmitter of Eversense is $995.02 with a free GoodRx coupon.0
                meter
                Meter
                DosageQuantityPrice as low asPrice per unit
                sensor holder1 meter$1487.02$1487.02
                smart transmitter1 meter$995.02$995.02

                Typical dosing for Eversense

                Your healthcare provider will insert Eversense under the skin of your upper arm once every 6 months. Replace the Eversense Smart Transmitter once a year.

                drug-cost

                How much does Eversense cost?

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                Eversense (brand)
                GoodRx lowest price

                $995.02

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                contraindications-icon

                Eversense contraindications

                Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Eversense will not be safe for you to take.

                1. Wearing the Smart Transmitter while getting a magnetic resonance imaging (MRI) procedure

                alternatives

                What are alternatives to Eversense?

                There are a number of medications that your doctor can prescribe in place of Eversense. Compare a few possible alternatives below.
                Eversense
                Used for:

                • Monitor glucose levels

                $995.02 Lowest GoodRx priceView Prices
                Dexcom G6
                Used for:

                • Monitor glucose levels

                $402.96 Lowest GoodRx priceView Prices
                FreeStyle Libre 3
                Used for:

                • Monitor glucose levels

                $89.35 Lowest GoodRx priceView Prices

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                References

                Best studies we found

                Ascensia Diabetes Care Holdings AG. (n.d.). Patient FAQs.

                Ascensia Diabetes Care Holdings AG. (n.d.). Onboarding videos.

                Ascensia Diabetes Care Holdings AG. (n.d.). The Eversense CGM app.

                View All References (6)

                Guidant. (2006). Sources of electromagnetic interference (EMI) for pacemakers, implantable cardioverter defibrillators (ICDs) and heart failure devices.

                Heinemann, L., et al. (2020). Benefits and limitations of MARD as a performance parameter for continuous glucose monitoring in the interstitial space. Journal of Diabetes Science and Technology.

                MedlinePlus. (2023). Electrocauterization.

                National Kidney Foundation. (n.d.). Lithotripsy.

                Senseonics, Inc. (2023). Eversense E3 user guide.

                U.S. Food and Drug Administration. (2014). Diathermy.

                GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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