Diclona Gel (diclofenac / lidocaine) is applied to the skin to relieve aches and pains temporarily from arthritis, sore muscles, and joints. It's a combination of two topical medications which can be found over-the-counter (OTC) individually (lidocaine and diclofenac). This combination is only available as a brand-name prescription medication, so it can be expensive.
Pain, discomfort, and soreness caused by:
Diclona Gel (diclofenac / lidocaine) is a combination of two different topical medications. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking proteins called cyclooxygenase 1 and 2 (COX-1 and COX-2) enzymes from making chemicals called prostaglandins. Prostaglandins play many roles in your body, including causing pain and swelling where you get injured. By blocking your body from making prostaglandins, this medication eases joint pain and swelling.
Diclona Gel (diclofenac / lidocaine) also contains lidocaine, which eases pain by numbing the nerves and making them less sensitive to pain or irritation. Lidocaine is a local anesthetic, meaning it only lowers pain in the area of skin closely around or directly in contact with the medication.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Application site reactions:
Contact your healthcare provider immediately if you experience any of the following.
You should only apply Diclona Gel (diclofenac / lidocaine) to skin that's not broken or damaged. Applying this medication to broken or inflamed skin can cause you to absorb more of the medication and raise your chance of experiencing side effects, such as skin irritations. You should also avoid getting Diclona Gel (diclofenac / lidocaine) in your eyes as this can cause serious eye irritation.
You're recommended to avoid the sun when using Diclona Gel (diclofenac / lidocaine). Though rare, the diclofenac in this medication can make your skin more sensitive to the sun. This can result in redness, irritation, or rash after sun exposure.
You're not recommended to use ibuprofen (Advil) tablets with Diclona Gel (diclofenac / lidocaine), unless your provider instructs you to do so. Both Ibuprofen (Advil) and the diclofenac in Diclona Gel (diclofenac / lidocaine) are nonsteroidal anti-inflammatory drugs (NSAIDs). Using these medications together puts you at higher risk for side effects, such as blood clots and swelling in the hands and feet. If Diclona Gel (diclofenac / lidocaine) alone isn't enough to treat your pain, discuss with your provider about other options for you. Please be aware that NSAIDs are found in many common over-the-counter and prescription pain medications. They sometimes appear in combination with other medications to treat different conditions, such as the common cold or trouble sleeping. Talk with your healthcare provider or pharmacist if you're not sure whether you're already taking an NSAID.
Yes, Diclona Gel (diclofenac / lidocaine) could potentially interact with certain medications. Ask your provider before using Diclona Gel (diclofenac / lidocaine) if you're taking medications to correct a heart rhythm problem. Certain heart rhythm medications, like mexiletine, can raise your chance of having serious side effects from Diclona Gel (diclofenac / lidocaine). Diclona Gel (diclofenac / lidocaine) also shouldn't be used with other local anesthetics, like benzocaine. Using multiple local anesthetics can raise your risk of serious side effects like methemoglobinemia, a problem in which your blood can't carry enough oxygen to the cells in your body.
Diclona Gel (diclofenac / lidocaine) might not be safe for people with serious liver problems. This is because the liver is responsible for breaking down lidocaine in the body. For this reason, lidocaine levels might get too high if this medication is used by people with liver problems. This can result in a higher risk for side effects from Diclona Gel (diclofenac / lidocaine).
Diclona Gel (diclofenac / lidocaine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Diclona Gel (diclofenac / lidocaine) can cause a condition known as methemoglobinemia where your blood can't get enough oxygen to your body. This is linked to the lidocaine in this product and it can be life-threatening. Your risk is higher if you have low G6PD, a condition passed down from parent to child, where your red blood cells tend to burst or break apart. Be careful using Diclona Gel (diclofenac / lidocaine) if you're around oxidizing chemicals, such as chlorine and hydrogen peroxide. These chemicals might be present in common household products like cleaning supplies and hair dye. Methemoglobinemia can occur immediately or within hours of using Diclona Gel (diclofenac / lidocaine). Earliest signs include headache, tiredness, and your skin turning blue. Get medical help right away to avoid more serious and life-threatening side effects like seizures, loss of consciousness, and heart rhythm problems (fast heart beat, dizziness, shortness of breath).
Nonsteroidal anti-inflammatory drugs (NSAIDs), like the diclofenac in Diclona Gel (diclofenac / lidocaine), can raise your risk of having blood clots, heart attacks, or strokes. This can happen early during treatment, but people using NSAIDs for a long time have a higher risk of this happening. That’s why it’s important to use the lowest possible dose for the shortest possible time. If you have heart problems, talk to your healthcare provider before starting this medication. Call 911 or get immediate medical help if you experience chest pain, trouble breathing, weakness on one side of your body, or trouble speaking or walking.
NSAIDs, such as diclofenac, might cause sudden, very serious, and sometimes life-threatening allergic and skin reactions. Symptoms include fever, body aches, rash, peeling skin, painful blisters all over your body, and swelling of the face. Stop Diclona Gel (diclofenac / lidocaine) and get help right away if you experience these symptoms.
The diclofenac in Diclona Gel (diclofenac / lidocaine) can cause your body to hold onto more water. This can lead to new or worsening existing heart failure and swelling of your arms and legs. Let your provider know if you notice any changes in your blood pressure or experience symptoms, such as trouble breathing, tiredness, swelling in your body, or sudden weight gain.
Don't use Diclona Gel (diclofenac / lidocaine) or other NSAIDs starting around the third trimester of pregnancy because doing so can lead to serious heart or kidney problems in your unborn baby. If you want to use Diclona Gel (diclofenac / lidocaine) in your second trimester, talk with your provider first to see if the benefit of pain relief is greater than the risk of kidney problems in your unborn baby. If you do need to use Diclona Gel (diclofenac / lidocaine) during your second trimester, make sure to use the lowest dose for the shortest period of time. If you're pregnant or thinking of getting pregnant, talk to your provider about the risks and benefits of using Diclona Gel (diclofenac / lidocaine).
The typical dose is to apply a thin film of Diclona Gel (diclofenac / lidocaine) to the affected area, up to 4 times daily.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Diclona Gel (diclofenac / lidocaine) will not be safe for you to take.
Pain, discomfort, and soreness caused by:
Topical lidocaine products come in many forms and strengths. Each can be used for different conditions.
In general, they're used for temporary relief of pain, itching, burning, or discomfort from: