Robitussin Medi-Soothers (dextromethorphan / menthol) is a combination medication that's used to relieve cough and mouth and throat pain for people 12 years and older. These lozenges contain a cough suppressant (dextromethorphan) and a pain reliever (menthol). The lozenges are typically dissolved slowly in the mouth every 4 hours as needed. Side effects aren't common but can include sleepiness and dizziness.
Short-term relief of:
Minor irritation in the mouth
Sore throat or mouth
Cough
Robitussin Medi-Soothers (dextromethorphan / menthol) is a combination of two medications.
Dextromethorphan is a cough suppressant. It works in the brain to lower your urge to cough.
Menthol is a pain reliever (analgesic). It's a chemical that's found in mint plants like peppermint. Menthol works by causing a cooling sensation and makes the nerves in your mouth and throat less sensitive to pain.
Source:Â DailyMed
Works well to treat mouth and throat pain and cough
Available over the counter
Easy to take with you wherever you go
Might need to take as often as every 4 hours to relieve symptoms
Might not be sugar free
Typically can't be used by young children under 12 years old
Place the lozenge in your mouth and let it melt slowly. As it melts, the medication will coat your mouth and throat to provide pain relief there. Don't chew on the lozenges.
If you need to take two Robitussin Medi-Soothers (dextromethorphan / menthol) lozenges each time, take one lozenge after the other. Don't place two lozenges into the mouth at the same time because this raises your risk of choking.
Robitussin Medi-Soothers (dextromethorphan / menthol) is only meant to relieve cough from minor throat or lung irritation caused by conditions like the common cold. Speak with your primary care provider first if you have a cough that lasts more than a week, a cough that's related to a breathing problem (e.g., asthma, emphysema), or a cough with a lot of mucus. You might need other treatment.
Stop taking Robitussin Medi-Soothers (dextromethorphan / menthol) and contact your primary care provider if your symptoms don't get better after a week or if they worsen. Also stop taking this product and speak to a healthcare professional if your cough comes back or occurs with a fever, rash, or headache. These might be signs of a more serious lung problem, such as bronchitis or pneumonia.
Speak to your primary care provider if your sore throat pain lasts for more than 2 days or if the pain is severe. Also speak with your primary care provider if you have a sore throat along with fever, headache, rash, swelling, nausea, or vomiting. These could be signs of a throat infection, like strep throat or tonsillitis, and you might need to take antibiotics to treat it.
Avoid drinking alcohol while you're taking Robitussin Medi-Soothers (dextromethorphan / menthol). Alcohol might worsen possible side effects, like stomach upset, dizziness, and sleepiness.
Tell your care team about all the medications you're taking, especially if you're taking monoamine oxidase inhibitors (MAOIs), which are a type of medication that's sometimes used for mood or Parkinson's disease. You shouldn't take Robitussin Medi-Soothers (dextromethorphan / menthol) at the same time as MAOIs or within 2 weeks of stopping the MAOI because of the risk for serotonin syndrome.
Carefully read package labels if you're taking Robitussin Medi-Soothers (dextromethorphan / menthol) along with other cough, cold, or allergy medications. Make sure you're not accidentally taking something else with dextromethorphan in it to avoid taking too much medication. Ask your pharmacist if you're not sure whether a product contains dextromethorphan.
Robitussin Medi-Soothers (dextromethorphan / menthol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Taking monoamine oxidase inhibitors (MAOIs) 14 days before taking Robitussin Medi-Soothers (dextromethorphan / menthol) | Taking other medications that raise serotonin levels in your brain
The dextromethorphan in Robitussin Medi-Soothers (dextromethorphan / menthol) can raise your risk for serotonin syndrome. This is a rare, but potentially life-threatening side effect that happens when there's too much serotonin in the brain. Get medical help right away if you have any symptoms of serotonin syndrome, including fast heart rate, sweating, muscle stiffness or spasms, high fever, and confusion.
Your risk for serotonin syndrome is higher if you're also taking other medications that affect serotonin levels, such as certain antidepressants, MAOIs, and certain migraine medications. Make sure your healthcare team knows about all the medications you take or plan to take. This include prescription medications, over-the-counter medications, and supplements. Your care team can make sure Robitussin Medi-Soothers (dextromethorphan / menthol) is safe to take with your other medications.
Robitussin Medi-Soothers (dextromethorphan / menthol) contains ingredients that can be found in many other over-the-counter cough and cold products. Using more than one product containing dextromethorphan can raise your risk of taking too much medication. This can lead to serious side effects, such as high blood pressure, heart rhythm problems, hallucinations (seeing things that aren't real), and even seizures and loss of consciousness.
To avoid accidentally taking too much, read package labels carefully. Ask your pharmacist if you're not sure whether a product has any similar ingredients as Robitussin Medi-Soothers (dextromethorphan / menthol). Get medical help as soon as possible or contact a poison control center at 1-800-222-1222 if you think you or your child has accidentally taken too much medication.
Each lozenge contains 5 mg of dextromethorphan and 5 mg of menthol.
Adults and children 12 years and older: The typical dose is 2 lozenges (one after the other) dissolved in the mouth every 4 hours as needed. Don't use more than 12 lozenges in a 24-hour period.
Children under 12 years old: Don't use. Ask your child's pediatrician for other options.
Currently take or have taken a monoamine oxidase inhibitor (MAOI) in the last 2 weeks
Short-term relief of:
Minor irritation in the mouth
Sore throat or mouth
Cough
Sore mouth and sore throat
Mouth irritation
Minor irritation, pain, sore throat, and sore mouth
Cough caused by minor throat irritation, like from a cold
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Folan, P., et al. (2020). What is menthol? American Thoracic Society.
Haleon US Holdings LLC. (2024). Robitussin Medi-Soothers- dextromethorphan hydrobromide, menthol lozenge [package insert]. DailyMed.
Journey, J. D., et al. (2023). Dextromethorphan toxicity. StatPearls.
Li, Z., et al. (2022). The distinctive role of menthol in pain and analgesia: Mechanisms, practices, and advances. Frontiers in Molecular Neuroscience.
Oh, S., et al. (2023). Dextromethorphan. StatPearls.
Spangler, D. C., et al. (2016). Dextromethorphan: A case study on addressing abuse of a safe and effective drug. Substance Abuse Treatment, Prevention, and Policy.
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