Typical dosage for Daptomycin
Daptomycin (Cubicin) is given as an injection into the veins (IV) by a provider in a healthcare setting (e.g., hospital, office, nursing home). The injection is typically given as an infusion that takes 30 minutes to an hour. But it can also be given as a quick injection over a 2-minute period for adults only.
Your dose is based on your body weight and kidney function. The dose and length of treatment also depends on what type of infection you have and how serious it is. Your provider will determine the right dose and length of treatment for you.
For most infections, the general dosage is as follows:
Skin and soft tissue infections
- Adults: The typical dose is 4 mg/kg IV once daily for 7 to 14 days.
- Children ages 1 to 17 years: The typical dose is 5 mg/kg to 10 mg/kg IV once daily for up to 14 days.
Bloodstream infections (caused by Staphylococcus aureus or "staph")
- Adults: The typical dose is 6 mg/kg IV once daily for 2 to 6 weeks.
- Children ages 1 to 17 years: The typical dose is 7 mg/kg to 12 mg/kg IV once daily for up to 6 weeks.

