Daclatasvir is a medication that's taken by mouth to treat hepatitis C infection. It's typically used once daily for 12 weeks. It has been discontinued by the manufacturer and is no longer available in the United States.
Daclatasvir is an antiviral medication used for the treatment of hepatitis C infection genotype 1 and 3. It works by attaching to NS5A, an important protein that helps the hepatitis C virus make more copies of itself. Once daclatasvir attaches to this specific protein of the virus, the medication stops the virus from growing. It's often used with Sovaldi (sofosbuvir) and sometimes with ribavirin (Rebetol) to help remove hepatitis C viruses from the body.
No, daclatasvir has been discontinued and is no longer available in the United States.
The manufacturer (Bristol Myers Squibb) voluntarily discontinued daclatasvir for business reasons. This medication wasn't taken off the market for safety concerns or lack of benefit.
There are many different factors that a provider must consider in choosing the right hepatitis C medication for you, such as your medical history, age, genotype of the hepatitis C virus, and if you have any liver problems. Several alternative medications are available, including Epclusa (sofosbuvir / velpatasvir) and Mavyret (glecaprevir / pibrentasvir), which are typically taken by mouth daily for 8 to 12 weeks. Keep in mind that these medications can cure 95% of people with hepatitis C. These medications can also help slow down liver damage due to the infection. Talk with your provider to determine which hepatitis C treatment is best for you.