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Daklinza

daclatasvir
Used for Hepatitis C
Used for Hepatitis C

Daclatasvir is a medication that's taken by mouth to treat hepatitis C infection. It's typically used once daily for 12 weeks. It has been discontinued by the manufacturer and is no longer available in the United States.

Reviewed by:
reviewer
Ally Tsai, PharmD
reviewer
Kristianne Hannemann, PharmD
Last reviewed on July 5, 2022
BasicsFAQsAlternativesPricesMedicare
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What is Daclatasvir?

What is Daclatasvir used for?

  • Chronic (long-term) hepatitis C infection genotype 1 or 3

How Daclatasvir works

Drug Facts

Common BrandsDaklinza (brand no longer available)
Drug ClassAntiviral
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityDiscontinued
faqs

Frequently asked questions about Daclatasvir

What is daclatasvir?
Daclatasvir is an antiviral medication used for the treatment of hepatitis C infection genotype 1 and 3. It works by attaching to NS5A, an important protein that helps the hepatitis C virus make more copies of itself. Once daclatasvir attaches to this specific protein of the virus, the medication stops the virus from growing. It's often used with Sovaldi (sofosbuvir) and sometimes with ribavirin (Rebetol) to help remove hepatitis C viruses from the body.
Is daclatasvir still available?
No, daclatasvir has been discontinued and is no longer available in the United States.
Why was daclatasvir discontinued?
The manufacturer (Bristol Myers Squibb) voluntarily discontinued daclatasvir for business reasons. This medication wasn't taken off the market for safety concerns or lack of benefit.
What other medications can I use instead of daclatasvir?
There are many different factors that a provider must consider in choosing the right hepatitis C medication for you, such as your medical history, age, genotype of the hepatitis C virus, and if you have any liver problems. Several alternative medications are available, including Epclusa (sofosbuvir / velpatasvir) and Mavyret (glecaprevir / pibrentasvir), which are typically taken by mouth daily for 8 to 12 weeks. Keep in mind that these medications can cure 95% of people with hepatitis C. These medications can also help slow down liver damage due to the infection. Talk with your provider to determine which hepatitis C treatment is best for you.
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alternatives

What are alternatives to Daclatasvir?

There are a number of medications that your doctor can prescribe in place of Daclatasvir. Compare a few possible alternatives below.
Daclatasvir
Used for:

  • Chronic (long-term) hepatitis C infection genotype 1 or 3

View Prices
Epclusa (sofosbuvir / velpatasvir)
Used for:

  • Chronic hepatitis C infection

$7796.63 Lowest GoodRx priceView Prices
Mavyret (glecaprevir / pibrentasvir)
Used for:

  • Chronic (long-term) hepatitis C genotype 1, 2, 3, 4, 5, or 6 infection in certain people age 3 years and older

  • Hepatitis C genotype 1 infection in people age 3 years and older who were previously treated with an NS5A inhibitor or an HCV protease inhibitor (not both)

$12851.80 Lowest GoodRx priceView Prices

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