The main symptom of chronic fatigue syndrome is in the name: tiredness. People with chronic fatigue syndrome may experience other symptoms in addition to or as a result of fatigue.
References
Centers for Disease Control and Prevention. (2021). Symptoms of ME/CFS.
Centers for Disease Control and Prevention. (2023). Myalgic encephalomyelitis/chronic fatigue syndrome.
MedlinePlus. (2023). Chronic fatigue syndrome.
Sapara, A., et al. (2023). Chronic fatigue syndrome. StatPearls.
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Written by:
Sophia KellerSophia Keller was an editorial intern on the GoodRx Health team. She has a bachelor’s degree in justice studies from Arizona State University.

Reviewed by:
Mera Goodman, MD, FAAPMera Goodman, MD, FAAP, is a board-certified pediatrician. Prior to practicing medicine, she worked as a management consultant.






