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COMT Inhibitors

COMT inhibitors are used to treat Parkinson's disease. They work by increasing levels of levodopa in the body.

Why are comt inhibitors prescribed?

Parkinson's Disease (100%)

How are these percentages calculated?

Key takeaways

COMT inhibitors are used to treat Parkinson's disease. They work by blocking catechol-O-methyltransferase (COMT), an enzyme (protein) that breaks down dopamine in the body. COMT inhibitors help levodopa-based medications last longer in the body. So you'll take them along with carbidopa / levodopa medications for Parkinson's disease. Examples of COMT inhibitors include entacapone (Comtan), opicapone (Ongentys), and tolcapone (Tasmar).

Prices for popular COMT Inhibitors medications

Viewing 3 of 3 medications

Comtan (entacapone)

as low as$84

ENTACAPONE treats the symptoms of Parkinson disease in people who are taking Levodopa. It works by increasing the amount of dopamine in your brain, a substance which helps manage body movements and coordination. This reduces the symptoms of Parkinson, such as body stiffness and tremors.

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Ongentys

as low as$684

OPICAPONE treats the symptoms of Parkinson disease in people who are taking Carbidopa; Levodopa. It works by increasing the amount of dopamine in your brain, a substance which helps manage body movements and coordination. This reduces the symptoms of Parkinson, such as body stiffness and tremors.

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Tasmar (tolcapone)

TOLCAPONE treats the symptoms of Parkinson disease in people who are taking Carbidopa; Levodopa. It works by increasing the amount of dopamine in your brain, a substance which helps manage body movements and coordination. This reduces the symptoms of Parkinson, such as body stiffness and tremors.

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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.