Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Zioptan (tafluprost) and timolol are both prescription eye drops used to lower eye pressure and treat glaucoma, but they belong to different drug classes and have some key differences. Zioptan is a prostaglandin that helps fluid drain from the eye, while timolol is a beta blocker that reduces the amount of fluid in the eye. Zioptan is typically used once daily in the evening and comes in single-use containers, whereas timolol is usually taken once or twice daily. Both medications are available in a lower-cost generic form. Zioptan can cause changes to your eyelashes and eye color, and it needs to be refrigerated until opened, unlike timolol. Timolol, on the other hand, can cause systemic side effects like lower blood pressure and heart rate, and it is not recommended for people with certain heart or lung conditions. Both medications can cause eye irritation, but timolol is more likely to cause burning or stinging right after application.
Zioptan (tafluprost)
Timolol
Zioptan (tafluprost)
Timolol
Summary of Zioptan vs. Timolol
Summary for Prostaglandin
Prescription only
Zioptan (tafluprost) is an eye drop medication used to treat high pressure in the eye, such as glaucoma. It works as a prostaglandin to help relieve pressure in the eye. Zioptan (tafluprost) is for adults and is used once each night. Side effects include feeling like there's something in the eye, burning, and stinging. Zioptan (tafluprost) is available as a brand-name and now also a generic medication.
Summary for Beta blocker
Prescription only
Timolol is an eye drop medication that's used to lower pressure within the eye and treat glaucoma. This medication belongs to the drug class called beta blockers. Timolol can be used by itself or together with other eye drops. The usual dosage is a drop of timolol into the eye(s) once or twice a day. Common side effects include burning or stinging after you put in the eye drops, but this is generally a temporary feeling. Although the brand name Timoptic was discontinued, the generic version is still available.