Zenpep vs. Creon for Pancreatic Insufficiency: Important Differences and Potential Risks.

Zenpep

(pancrelipase)

Creon

(pancrelipase)

Summary for Zenpep

Prescription only

Zenpep (pancrelipase) is a prescription medication used for children and adults with exocrine pancreatic insufficiency (EPI), a condition where the pancreas doesn’t make enough enzymes to digest food. It contains pancreatic enzymes that help break down fats, carbohydrates, and proteins so your body can absorb nutrients. You take the capsule by mouth with every meal and snack, and your dose is based on your weight, age, and diet. Common side effects include cough, headache, and feeling full quickly. Right now, there isn’t a generic version of Zenpep (pancrelipase) available.

Indications for Zenpep

Exocrine pancreatic insufficiency

Pros and Cons for Zenpep

Pros

Capsules can be opened up and mixed with certain soft foods
Safe for children and infants
Comes in multiple strengths
No known interactions with other medications

Cons

Must be taken with every meal and snack
Might not be safe to take for people with pork allergy
Can cause stomach pain and vomiting
Dose adjustment can take a while

Common Side Effects for Zenpep

Adults and children 7 years and older with cystic fibrosis:

Headache (15%)
Bruising (6%)
Cough (6%)
Feeling full soon after eating (6%)

Children 1 to 6 years old with cystic fibrosis:

Stomach pain
Fatty stools

Warnings for Zenpep

Scarring in the colon (fibrosing colonopathy)
Mouth irritation
High uric acid levels
Possible risk of infection
Severe allergic reaction

Summary for Creon

Prescription only

Creon (pancrelipase) is a prescription medication that contains pancreatic enzymes to help you digest food if your body doesn't make enough of them. It's used in both children and adults to treat exocrine pancreatic insufficiency (EPI). The medication comes as a pill that you take by mouth with every meal and snack to help break down food. The dose depends on your weight, age, and how much fat you eat, and it might be adjusted over time. Common side effects include cough, stomach pain, and vomiting.

Indications for Creon

Exocrine pancreatic insufficiency (EPI)

Pros and Cons for Creon

Pros

Capsules can be opened up and mixed with certain soft foods
Safe for children and infants
Comes in multiple strengths
No known interactions with other medications

Cons

Must be taken with every meal and snack
Might not be safe to take for people with pork allergy
Can cause stomach pain and vomiting
Dose adjustment can take a while

Common Side Effects for Creon

Adults and children 7 years and older with cystic fibrosis:

Vomiting (6%)
Dizziness (4%)
Cough (4%)

Children ages 4 months to 6 years old with cystic fibrosis:

Vomiting (6%)
Irritability (6%)
Reduced appetite (6%)

Adults with chronic pancreatitis or pancreas removal surgery:

High blood sugar (8%)
Low blood sugar (4%)
Stomach pain (4%)
Abnormal stool (4%)
Passing gas (4%)
Frequent bowel movements (4%)
Common cold symptoms (4%)

Warnings for Creon

Scarring in the colon (fibrosing colonopathy)
Mouth irritation
High uric acid levels
Possible risk of infection
Severe allergic reactions

Prices with our coupons for Zenpep vs. Creon

Zenpep100 capsules / 40000 units

$1,627.25$2,116.09

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Creon100 capsules / 36000 units

$1,278.11$1,655.41

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Zenpep vs. Creon

Zenpep

Creon

Summary for Zenpep

Indications for Zenpep

Pros and Cons for Zenpep

Pros

Cons

Common Side Effects for Zenpep

Warnings for Zenpep

Summary for Creon

Indications for Creon

Pros and Cons for Creon

Pros

Cons

Common Side Effects for Creon

Warnings for Creon

Prices with our coupons for Zenpep vs. Creon

Compare other Pancreatic Insufficiency drugs

Browse medications by letter

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Zenpep

Creon

Summary for Zenpep

Indications for Zenpep

Pros and Cons for Zenpep

Pros

Cons

Common Side Effects for Zenpep

Warnings for Zenpep

Summary for Creon

Indications for Creon

Pros and Cons for Creon

Pros

Cons

Common Side Effects for Creon

Warnings for Creon