Vinblastine
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Vincristine
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Summary for Vinblastine
Vinblastine is a chemotherapy medication. It’s used to treat many types of cancer, including Hodgkin lymphoma and mycosis fungoides. It works as a microtubule inhibitor, or a “vinca alkaloid,” to kill cancer cells and stop the cancer from spreading. Vinblastine is given as an infusion through the vein (IV) at a medical center. It can cause side effects like a low blood cell count, hair loss, and constipation. Vinblastine is usually given along with other chemotherapy medications as part of a treatment plan.
Indications for Vinblastine
Pros and Cons for Vinblastine
Pros
- Each injection takes just a few minutes (up to 15 minutes)
- Low risk of nausea and vomiting
Cons
- Given as an injection through the vein at a medical center
- Often causes low blood cell counts, which can make it easier for you to get sick
- Might cause uncomfortable side effects, like constipation and numbness in fingers and toes
Common Side Effects for Vinblastine
- Low white blood cells
- Low red blood cells (anemia)
- Low platelets
- Hair loss
- Constipation
- High blood pressure
- Feeling unwell
- Weakness
- Bone pain
- Jaw pain
- Pain where the cancer is
Warnings for Vinblastine
- Must only be given as an intravenous (IV) injection by a trained healthcare professional
- Skin and tissue damage around IV area
- Harm to an unborn baby
- Low blood cell counts
- Lung problems
- Possible problem with the nervous system
Summary for Vincristine
Vincristine is a chemotherapy medication that helps treat many different kinds of cancer. This includes acute leukemia, Hodgkin’s lymphoma, non-Hodgkin’s lymphomas, and other cancers. The medication works as a microtubule inhibitor, or “vinca alkaloid.” It stops the cancer from growing by destroying cancer cells in the body. Vincristine is given as an infusion through the vein at a medical center. It's common to have constipation as a side effect. You can also feel numbness, pain, and tingling in the fingers and toes. Vincristine is usually given with other cancer treatments.
Indications for Vincristine
- Acute leukemia
- Hodgkin’s lymphoma
- Non-Hodgkin’s lymphomas
- Rhabdomyosarcoma
- Neuroblastoma
- Wilms’ tumor (a type of kidney cancer)
Pros and Cons for Vincristine
Pros
- Typically given once a week
- A part of recommended treatment plans for acute lymphoblastic leukemia, Hodgkin’s lymphoma, and non-Hodgkin’s lymphoma
Cons
- Given as an infusion through the vein
- Can cause nerve problems and hair loss
Common Side Effects for Vincristine
- Nerve pain
- Numbness or tingling in the fingers or toes (peripheral neuropathy)
- Feeling very weak
- Constipation
- Nausea
- Vomiting
- Diarrhea
- Stomach pain or cramps
- Hair loss
- Trouble walking or moving
- Problems with urination
Warnings for Vincristine
- Pain and tissue damage around the infusion site
- For IV use only
- Nerve problems
- Problems with the digestive system, including constipation
- Low blood cell counts
- Liver problems
- Lung problems
- Harm to an unborn baby
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