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Urispas vs. Elmiron

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Flavoxate (Urispas) and Elmiron (Pentosan) are both used to treat urinary-related symptoms, but they have different uses and mechanisms. Flavoxate is an anticholinergic and antispasmodic that helps relieve urinary symptoms like painful urination and urgency caused by urinary or prostate infections. It works by relaxing the muscles around your urinary tract. On the other hand, Elmiron is a urinary analgesic used to treat bladder pain and discomfort caused by bladder pain syndrome (interstitial cystitis). Its exact mechanism isn't fully understood, but it is believed to protect the bladder lining from irritating substances in the urine. Flavoxate works quickly, within 55 minutes, but must be taken 3 to 4 times a day, while Elmiron can take 3 to 6 months to show effects and is taken 3 times a day on an empty stomach. Flavoxate is available as a lower-cost generic, whereas Elmiron is the only FDA-approved oral medication for bladder pain syndrome. Both medications have side effects, but Elmiron has specific risks like potential permanent eye damage and increased bleeding risk.

Flavoxate

 

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Elmiron

(pentosan)

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Summary for Urispas

Prescription only

Flavoxate treats urinary symptoms that you experience when you have a urinary or prostate infection. It cannot cure the infection on its own, but it can be used together with an antibiotic for treatment of an infection.

Indications for Urispas

  • Relieves urinary symptoms, such as painful urination, urinary urgency, frequency, loss of bladder control, frequent urination at night, and lower stomach pain, that you experience with urinary and prostate infections

Pros and Cons for Urispas

Pros

  • Works quickly (in 55 minutes) to relieve your urinary symptoms
  • Available as a lower-cost, generic medication

Cons

  • Only treats your urinary symptoms (not your infection), so it must be taken with another medication to treat your urinary or prostate infection
  • Taken 3 to 4 times per day
  • Generally not recommended in people 65 years and older
  • Cannot be used for people with active bleeding in their stomach
  • Hasn’t been studied in children less than 12 years old so it’s unclear if it’s safe or even works for them

Warnings for Urispas

  • Changes to your vision

Summary for Elmiron

Prescription only

Elmiron (pentosan) is a urinary analgesic used to treat bladder pain and discomfort caused by bladder pain syndrome (interstitial cystitis). This medication has been studied in people 16 years and older. The usual dosage is 1 capsule taken by mouth three times a day. Potential side effects include nausea and hair loss. More serious side effects can include eye damage like changes in the retina and vision problems.

Indications for Elmiron

Pros and Cons for Elmiron

Pros

Cons

  • Must be taken 3 times per day
  • Can take 3 to 6 months to start working
  • Needs to be taken on an empty stomach

Common Side Effects for Elmiron

  • Hair loss (4%)
  • Diarrhea (4%)
  • Nausea (4%)
  • Headache (3%)
  • Rash (3%)
  • Stomach pain (2%)
  • Upset stomach (2%)
  • Abnormal liver tests (1%)
  • Dizziness (1%)

Warnings for Elmiron

  • Changes in the retina of the eye (pigmentary maculopathy)
  • Risk of bleeding
  • Risk of liver problems

Prices with our coupons for Urispas vs. Elmiron

Price Card Drug Icon
Flavoxate30 tablets / 100mg
$21.69$49.29
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Price Card Drug Icon
Elmiron90 capsules / 100mg
$1,092.59$1,287.87
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