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Compare Tyenne vs. Actemra

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Tyenne (tocilizumab)
    Actemra (tocilizumab)
  • Tyenne (tocilizumab)
    Actemra (tocilizumab)

  • Summary of Tyenne vs. Actemra

    Summary for IL-6 receptor antagonist
    Prescription only

    Tyenne (tocilizumab or tocilizumab-aazg) is a biologic medication and a biosimilar to Actemra (tocilizumab). It helps lower inflammation in certain autoimmune conditions like rheumatoid arthritis and juvenile idiopathic arthritis. It's also FDA approved to treat other conditions, including giant cell arteritis and COVID-19. Tyenne (tocilizumab) is given as an injection either under the skin or into a vein, depending on your condition. Common side effects include upper respiratory infections, headache, and injection‑site reactions.

    Summary for IL-6 receptor antagonist
    Prescription only

    Actemra (tocilizumab) is an interleukin-6 (IL-6) receptor antagonist. It treats several inflammatory conditions in children and adults, including rheumatoid arthritis. It works by blocking IL-6, a chemical released by the immune system that causes inflammation and fever. Actemra (tocilizumab) is given as an injection (either through the veins or under the skin), typically weekly or every few weeks, depending on the condition you're taking it treat. Side effects include a higher risk of infections and headache.

  • Indications of Tyenne vs. Actemra

    Indications for
    •Moderate-to-severe rheumatoid arthritis (RA) - adults
    •Giant cell arteritis (GCA) - adults
    •Polyarticular juvenile idiopathic arthritis (PJIA) - adults and children 2 years and older
    •Systemic juvenile idiopathic arthritis (SJIA) - adults and children 2 years and older
    •Cytokine release syndrome (CRS) - adults and children 2 years and older
    •COVID-19 infection - adults
    Indications for
    •Moderate-to-severe rheumatoid arthritis (RA) - adults
    •Giant cell arteritis (GCA) - adults
    •Systemic sclerosis-associated interstitial lung disease (SSc-ILD) - adults
    •Polyarticular juvenile idiopathic arthritis (PJIA) - adults and children 2 years and older
    •Systemic juvenile idiopathic arthritis (SJIA) - adults and children 2 years and older
    •Cytokine release syndrome (CRS) - adults and children 2 years and older
    •COVID-19 infection - adults and children 2 years and older

  • Pros and Cons of Tyenne vs. Actemra

    Pros and Const for IL-6 receptor antagonist
    Pros
    •Can help multiple inflammatory autoimmune conditions
    •Given every 1 to 4 weeks, depending on the condition being treated
    •Available as an IV or SC injection
    Cons
    •Raises your risk for serious infections
    •Can affect your liver, so regular blood tests are needed
    •Not recommended during pregnancy or breastfeeding
    Pros and Const for IL-6 receptor antagonist
    Pros
    •Typically given every 1 to 4 weeks
    •Can be used in children age 2 years and older (for some conditions)
    •Comes as a prefilled syringe or autoinjector for easy at-home injections under the skin
    Cons
    •Needs to be given by an injection only
    •Can cause liver problems
    •Raises your risk for infections because it weakens your immune system

  • Common Side Effects of Tyenne vs. Actemra

    Common Side Effects for
    •Upper respiratory tract infections (up to 7%)
    •Common cold symptoms (up to 7%)
    •Headache (up to 7%)
    •High blood pressure (up to 6%)
    •Higher liver enzymes (up to 6%)
    •Injections-site reactions

    ^*The side effects listed above were reported in clinical trials where IV Tyenne (tocilizumab) was used to treat rheumatoid arthritis.^

    Common Side Effects for
    •Upper respiratory tract infections (up to 7%)
    •Headache (up to 7%)
    •High blood pressure (up to 6%)
    •Higher liver enzymes (up to 6%)

    Note: The side effects you experience might differ depending on why you're taking Actemra (tocilizumab) and whether you're receive it IV or SC.

  • Warnings of Tyenne vs. Actemra

    Common Side Effects for
    •Serious infections
    •Tears in the stomach or intestines
    •Liver problems
    •Low blood cell counts
    •High cholesterol and triglycerides
    •Cancer
    •Severe allergic reactions
    •Nerve problems
    •Vaccines
    Common Side Effects for
    •Risk of serious infections
    •Stomach tears and blockage
    •Worsening liver problems and risk of liver failure
    •Severe allergic reactions
    •Lower white blood cell (WBC) and platelet counts
    •High cholesterol
    •Serious allergic reactions
    •Vaccines

  • Prices with our coupons for Tyenne vs. Actemra

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    Learn more about Actemra

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