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Susvimo vs. Lucentis

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Susvimo

(ranibizumab)

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Lucentis

(ranibizumab)

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Summary for Susvimo

Prescription only

Susvimo (ranibizumab) is an eye implant for adults with wet age-related macular degeneration (AMD). It's also approved for adults with diabetic macular edema (DME) or diabetic retinopathy (DR). This medication works as a vascular endothelial growth factor (VEGF) inhibitor. You can only get this eye implant if you've already done well with at least two eye injections of a VEGF inhibitor. Once placed in the eye, the implant releases medication over several months before it needs to get refilled at an eye specialist's office. This helps you need fewer eye injections. But side effects can include blood spots on the eye and eye pain.

Indications for Susvimo

Pros and Cons for Susvimo

Pros

  • Only need to get the implant refilled every 6 or 9 months, depending on your eye condition
  • Can't see the implant in the eye
  • Helps you need fewer eye injections per year for treating wet AMD, DME, or DR
  • Can help maintain vision over several months

Cons

  • Must have a surgical procedure to place (or remove) the implant into your eye
  • Must have already done well with two VEGF inhibitor injections in your eye before you can get this eye implant
  • Can make eyesight less clear or sharp during the months right after getting the implant
  • Raises your risk of a serious eye infection

Common Side Effects for Susvimo

  • Blood spot in the eye (62%)
  • Red eye (15%)
  • Swelling of the colored part of your eye (14%)
  • Eye pain (13%)
  • Cataract (11%)
  • Eye bleb (a fluid-containing blister in your eye; 8%)
  • Headache (6%)
  • Eye floaters (4%)

Warnings for Susvimo

  • Eye infection (endophthalmitis)
  • Separation of the retina from the back of the eye (retinal detachment)
  • Movement of the implant in the eye
  • Bleeding in the eye
  • Eye damage
  • Possible vision problems after the implant procedure

Summary for Lucentis

Prescription only

Lucentis (ranibizumab) is a medication used to prevent vision loss and blindness due to certain eye conditions such as macular degeneration or diabetic macular edema. It's given by a healthcare provider as an injection into your eye about once a month. There are two FDA-approved biosimilar medications to Lucentis (ranibizumab) called Byooviz and Cimerli.

Indications for Lucentis

Conditions related to swelling or damage to the macula or retina (parts of the eye that are important for vision):

Lucentis and all its biosimilars

  • Neovascular (wet) age-related macular degeneration (AMD)
  • Macular edema following retinal vein occlusion (RVO)
  • Myopic choroidal neovascularization (mCNV)

Lucentis and Cimerli biosimilar only

  • Diabetic macular edema (DME)
  • Diabetic retinopathy (DR)

Pros and Cons for Lucentis

Pros

  • Prevents blindness due to various eye conditions
  • Usually taken once a month
  • Has two biosimilars that work similarly to Lucentis (ranibizumab)

Cons

  • Injected into the eye, and it can cause pain and bleeding
  • Must be given by a provider in a clinic or hospital
  • Can be expensive if not covered by insurance

Common Side Effects for Lucentis

  • Bleeding on the outer surface of the eye (up to 74%)
  • Eye pain (up to 35%)
  • Floaters in the eye fluid (up to 27%)
  • High eye pressure (up to 24%)

Warnings for Lucentis

  • Eye infection and damage
  • High eye pressure
  • Blood clots
  • Higher risk of death in people with eye problems related to diabetes

Prices with our coupons for Susvimo vs. Lucentis

Price Card Drug Icon
Susvimo1 vial / 1ml of 100mg/ml
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Price Card Drug Icon
Lucentis1 vial / 0.05ml of 0.5mg
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