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Dayquil vs. Phenylephrine

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Dayquil Cold and Flu

 

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phenylephrine eye drops

 

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Summary for Dayquil

Over-the-counter

Dayquil Cold and Flu is a combination of three active ingredients: acetaminophen (an analgesic), dextromethorphan (a cough suppressant), and phenylephrine (a decongestant). Dayquil Cold and Flu helps treat symptoms from the common cold and flu in adults and children. It can relieve stuffy nose, cough, sore throat, headache, aches, and fever. Besides Dayquil Cold and Flu, this medication is available under many other brand names and as a generic. It's available as pills and a liquid that's typically taken every 4 hours. Side effects aren't common but can include stomach upset and nervousness.

Indications for Dayquil

  • Short-term relief of symptoms from the common cold and flu:
    • Minor aches and pains
    • Headache
    • Stuffy nose (nasal congestion)
    • Cough
    • Sore throat
    • Fever

Pros and Cons for Dayquil

Pros

  • Can treat a wide variety of common cold or flu symptoms
  • More convenient to take three medications in a single dose
  • Available over the counter and as a lower-cost generic
  • Alcohol-free liquid forms of the medication are available

Cons

  • Might need to take as often as every 4 hours to relieve symptoms
  • More difficult to customize the dose since Dayquil Cold and Flu is a fixed combination of three medications
  • Might not be the best choice for people with certain medical conditions, such as high blood pressure
  • Might not be the best choice for people who drink alcohol regularly

Common Side Effects for Dayquil

Warnings for Dayquil

  • Liver damage
  • Allergic skin reactions
  • Serotonin syndrome
  • Accidentally taking too much medication
  • Worsening of certain medical conditions

Summary for Phenylephrine

Prescription only

Phenylephrine eye drops are used to dilate (widen) pupils for eye exams or certain eye procedures. Side effects include temporary burning or stinging in the eye, blurry vision, and possibly raise your blood pressure. Let your provider know if your pregnant or breastfeeding because you might need to use a different medication.

Indications for Phenylephrine

  • Dilate (widen) pupils

Pros and Cons for Phenylephrine

Pros

  • Can be used in adults and children
  • Starts working quickly (within 15 minutes)
  • Available as a lower-cost generic medication

Cons

  • Can cause eye pain and stinging
  • Dilating effects can last for up to 7 hours (or longer)
  • The 10% strength can raise blood pressure in people with certain heart or thyroid problems

Common Side Effects for Phenylephrine

  • Temporary stinging or burning in your eye
  • Temporary blurry vision
  • Sensitivity to light

Warnings for Phenylephrine

  • For use in the eyes only
  • Heart problems
  • High blood pressure
  • Rebound pupil constriction

Prices with our coupons for Dayquil vs. Phenylephrine

Price Card Drug Icon
Dayquil24 capsules / 325mg/10mg/5mg
$10.68$14.97
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Phenylephrine1 eye dropper / 2ml of 2.5%
$21.67$40.99
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