Key takeaways
Seysara (sarecycline) and minocycline (Minocin) are both tetracycline antibiotics, but they have some key differences. Seysara is specifically used to treat moderate-to-severe non-nodular acne in people aged 9 and older, while minocycline treats moderate-to-severe acne as well as a broad range of bacterial infections, such as respiratory and urinary tract infections and sexually transmitted infections. Seysara is taken once daily, whereas minocycline dosing can vary, often requiring multiple doses per day. Seysara tends to have fewer side effects, with nausea being the most common, while minocycline can cause headaches and dizzines. Additionally, minocycline can cause your nails and skin to darken and can interact with birth control pills. Minocycline is avalable in the generic form, while Seysara is only available as a brand-name medication. Both medications should be avoided during pregnancy and breastfeeding due to potential harm to the baby.
