Key takeaways
Senna-S (docusate/senna) and Senokot (senna) are both over-the-counter medications used to treat occasional constipation, but they have some key differences. Senna-S is a combination of a stool softener (docusate) and a stimulant laxative (senna), which means it helps soften the stool and stimulate bowel movements. On the other hand, Senokot contains only senna, a stimulant laxative that works by stimulating the muscles in your intestines to help push out stools. Both medications are typically recommended to be taken at bedtime to produce a bowel movement by morning, and can be used daily if needed, but not for more than a week without consulting a provider. Both medications also work within 6 to 12 hours, but it are not recommended for long-term use. Both medications can cause stomach cramps, and may also lead to electrolyte changes if misused. While Senna-S combines two medications for a dual action, Senokot is a single-agent stimulant laxative.
