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Senexon-s vs. Metamucil

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Senna-S (docusate/senna) and Metamucil (psyllium) are both over-the-counter medications used to treat occasional constipation, but they work in different ways. Senna-S combines a stool softener (docusate) and a stimulant laxative (senna). Docusate draws water into your intestines to soften your stool, while senna stimulates your intestines to help push the stool out. In contrast, Metamucil is a bulk-forming fiber laxative that helps your stool absorb and hold onto water, making it bigger and softer for easier passage. Senna-S typically works within 6 to 12 hours and is often taken at night, while Metamucil can take 12 to 72 hours to relieve constipation and can be taken at any time of the day. Senna-S should be used short-term and can cause stomach cramps and loose stools, whereas Metamucil requires a lot of liquid to prevent choking and can cause bloating. Both medications are available in various forms and do not require a prescription.

Docusate/senna

 

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Psyllium

(Metamucil)

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Summary for Senexon-s

Over-the-counter

Docusate/senna is a combination medication containing docusate and senna. The two laxatives work together to treat constipation.

Indications for Senexon-s

  • Occasional constipation

Pros and Cons for Senexon-s

Pros

  • Contains two medications, so there's fewer pills and can sometimes be cheaper
  • Available over-the-counter so you don't need a prescription from your provider
  • Works fast to help you have a bowel movement

Cons

  • Should only be used short-term (less than 7 days)
  • Some people have stomach cramps
  • Can cause loose, watery stools

Common Side Effects for Senexon-s

See Risks and Warnings

Warnings for Senexon-s

  • Complete or partial blockage of intestines
  • Self-medication

Summary for Metamucil

Over-the-counter

Psyllium or psyllium husk is an over-the-counter (OTC) fiber supplement. It helps with occasional constipation in adults and children. This fiber laxative most often comes as a powder that's mixed with a beverage. But it can also come in capsules that you swallow. You take this laxative by mouth, up to 3 times a day if needed. Some side effects include gas, nausea, and bloating. Metamucil is a common brand name, but there are other brand-name and generic versions.

Indications for Metamucil

Pros and Cons for Metamucil

Pros

  • Powder can come in orange flavor with some sugar-free options
  • Also available as capsules, for people who don't like the powder or find it inconvenient
  • Available OTC so you don't need a prescription

Cons

  • Must take with a lot of liquid so you don't choke on the medication
  • Can take 12 to 72 hours to relieve constipation
  • Can cause bloating, especially when you first start

Common Side Effects for Metamucil

  • Change in bowel habits
  • Bloating

Warnings for Metamucil

  • Risk of choking
  • Caution use in people with phenylketonuria (PKU) - flavored powders only

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