Rivfloza
(nedosiran)
Get free couponsOxlumo
(lumasiran)
Get free couponsSummary for Rivfloza
Rivfloza (nedosiran) is an injectable medication that's used to lower oxalate levels in the urine in people 9 years and older with a rare inherited, genetic condition called primary hyperoxaluria type 1 (PH1). This medication belongs to the drug class called small interfering RNA (siRNA). It works to stop the liver from making oxalate. Rivfloza (nedosiran) is injected under the skin once a month. The most common side effect is having an injection site reaction. Rivfloza (nedosiran) is a brand-name medication; it isn't available as a lower-cost generic.
Indications for Rivfloza
- To lower oxalate levels in the urine in people 9 years and older with primary hyperoxaluria type 1 (PH1)
Pros and Cons for Rivfloza
Pros
- Can give at home after you get trained on how to inject the medication yourself
- Only need to take once per month
- Available in a prefilled syringe for convenience
Cons
- Injections can be uncomfortable
- Doesn't cure PH1; only helps to control symptoms
- Not approved for children younger than 9 years old
Common Side Effects for Rivfloza
- Injection site reaction (e.g., redness, pain, bruising, rash; 39%)
Summary for Oxlumo
Oxlumo (lumasiran) is an injectable medication used to treat a rare condition called primary hyperoxaluria type 1 (PH1). This condition mainly affects the kidneys, but can also harm other organs. Oxlumo (lumasiran) doesn't have many side effects and is given every 1 or 3 months, depending on your weight.
Indications for Oxlumo
- Lower the oxalate levels in people with primary hyperoxaluria type 1 (PH1)
Pros and Cons for Oxlumo
Pros
- Works well to lower oxalate levels in people with PH1
- Given every 1 or 3 months
- Not a lot of side effects
- Can use for adults and children of all ages
Cons
- Needs to be given by a healthcare provider
- Injections might be uncomfortable.
- Likely need to take for the rest of your life since PH1 is a genetic problem
- No lower-cost generic available
Common Side Effects for Oxlumo
- Injection site reactions (redness, pain, itching, swelling; 38%)
- Stomach pain (15%)
Prices with our coupons for Rivfloza vs. Oxlumo
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