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Neptazane vs. Trusopt

Methazolamide is used to help lower eye pressure and treats eye conditions like glaucoma in adults. It belongs to the drug class called carbonic anhydrase inhibitors. Methazolamide is a tablet that's taken by mouth, and the dosage is taken 2 or 3 times a day. This medication has many potential side effects, including tingling in the arms or legs, ringing in the ears, and stomach upset. There are possible interactions with aspirin and steroids.

• High pressure in the eye, such as with glaucoma

• Tingling or "pins and needles" feeling in the arms or legs
• Ringing in the ears
• Weakness
• Tiredness
• Loss of appetite
• Taste changes
• Nausea
• Vomiting
• Diarrhea
• More urination
• Vision changes

• Severe allergic reactions
• Interaction with aspirin
• Use with caution in people with breathing or lung problems

Dorzolamide is an eye drop medication used to treat high pressure in the eye in people with glaucoma or ocular hypertension. The dosage is 1 drop applied directly into the affected eye(s) three times per day. It's available as a generic only as the brand-name medication Trusopt has been discontinued. Dorzolamide is a sulfa medication, so it might not be the best choice if you have a serious sulfa allergy. Side effects include burning or stinging in the eye and a bitter taste in the mouth.

Treatment of high pressure in the eye in people with:

• Ocular hypertension
• Open-angle glaucoma

• Burning or stinging in the eye (33%)
• Bitter taste (25%)
• Bacterial eye infection (10-15%)
• Allergic reaction in the eye (10%)

• Severe allergic reactions
• Risk for eye infection (from contamination)
• Risk for swelling of the cornea