Natesto vs. Testosterone for Testosterone Replacement: Important Differences and Potential Risks.

Natesto

testosterone gel

Summary for Natesto

Prescription only

Natesto is a prescription testosterone nasal gel that's applied to the inside of the nose. It's a testosterone replacement therapy that's FDA approved to treat adult males with low testosterone levels. You'll have to apply it to each nostril 3 times a day. Common side effects include headache, runny nose, and nosebleeds. The medication only comes as a brand-name medication since no generic version is available.

Indications for Natesto

Low testosterone (also called hypogonadism)

Pros and Cons for Natesto

Pros

Absorbed quickly within in your body
Compared to testosterone gel, there’s a lower risk of accidentally exposing others to testosterone
Doesn't drip out because it's a gel
Can be applied within seconds

Cons

Causes nasal side effects like runny nose and nosebleeds
Needs to be used 3 times a day
Can't be used if you have nasal or sinus problems
Only available as a brand-name medication

Common Side Effects for Natesto

Rise in prostate-specific antigen (PSA, 5%)
Headache (4%)
Runny nose (4%)
Nosebleed (4%)
Nasal discomfort (4%)
Common cold symptoms (4%)
Bronchitis (4%)
Upper respiratory tract infection (4%)
Swelling of the nasal passages (4%)
Nasal scab (4%)

Warnings for Natesto

Nasal side effects
Risk of blood clots, including heart attack or stroke
Prostate problems
Potential for misuse, dependency, and addiction
Liver problems
Swelling in the legs or arms (edema)
Sleep apnea
High calcium levels in the blood

Summary for Testosterone

Prescription only

Testosterone gel is a prescription topical medication used to treat men with low testosterone. It helps raise testosterone levels when your body doesn't make enough naturally. You typically apply it once a day to your skin. Depending on the product, the gel comes in packets, pumps, or tubes. Some side effects include skin irritation, mood changes, and headache.

Note: This medication is available under several brand names, including AndroGel, Testim, and Vogelxo as well as in generic versions. Each might have different strengths, application sites, and instructions.

Indications for Testosterone

Low testosterone (also called hypogonadism)

Pros and Cons for Testosterone

Pros

Works well to raise testosterone levels
Applied once a day to your skin
Available in tubes, packets, or as a pump

Cons

Can cause skin irritation
Must avoid skin-to-skin transfer to other people
Need to wait hours before you can shower, swim, or bathe

Common Side Effects for Testosterone

AndroGel 1.62%

Rise in prostate-specific antigen (PSA) (11%)

AndroGel 1%

Acne (1-8%)
Abnormal lab tests (3-6%)
Skin irritation (3-5%)
Prostate problems (3-5%)

Testim

Skin irritation (2-4%)
Rise in red blood cell count (1-2%)

Vogelxo

Skin irritation (2-4%)
Rise in red blood cell count (1-2%)

Warnings for Testosterone

Risk of testosterone gel spreading to others
Higher red blood cell count
Blood clots
Worsening of enlarged prostate and risk of prostate cancer
Higher blood pressure
Potential for misuse, addiction, and dependency
Lower sperm count
Liver problems
Swelling in the arms and legs (edema)
Enlarged breasts
Breathing problems during sleep (sleep apnea)
Changes in cholesterol levels
High calcium levels

Prices with our coupons for Natesto vs. Testosterone

Natesto3 pumps / 11g of 5.5mg per actuation

$165.00$1,023.05

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Testosterone1 pump / 88g of 1.62%

$39.81$498.93

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Natesto vs. Testosterone

Natesto

testosterone gel

Summary for Natesto

Indications for Natesto

Pros and Cons for Natesto

Pros

Cons

Common Side Effects for Natesto

Warnings for Natesto

Summary for Testosterone

Indications for Testosterone

Pros and Cons for Testosterone

Pros

Cons

Common Side Effects for Testosterone

Warnings for Testosterone

Prices with our coupons for Natesto vs. Testosterone

Browse medications by letter

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Natesto

testosterone gel

Summary for Natesto

Indications for Natesto

Pros and Cons for Natesto

Pros

Cons

Common Side Effects for Natesto

Warnings for Natesto

Summary for Testosterone

Indications for Testosterone

Pros and Cons for Testosterone

Pros

Cons

Common Side Effects for Testosterone

Warnings for Testosterone