Menest
(esterified estrogens)
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Summary for Menest
Menest (esterified estrogens) is an estrogen hormone replacement used to relieve menopause symptoms like hot flashes and vaginal dryness. It's also used to treat low estrogen levels and certain advanced prostate and breast cancers. The tablet is taken by mouth, and dosage depends on why you're taking it. Menest (esterified estrogens) is only available as a brand-name medication since there is no generic version. Potential side effects include breast tenderness, nausea, and headache.
Indications for Menest
- Hot flashes, night sweats, and flushes from menopause
- Vaginal dryness and irritation from menopause
- Low estrogen from hypogonadism
- Low estrogen from castration (removal of the ovaries)
- Primary ovarian failure (ovaries stop working before age 40)
- Certain advanced breast cancers
- Certain advanced advanced prostate cancers
Pros and Cons for Menest
Pros
- Relieves multiple menopause symptoms
- Also treats low estrogen conditions and certain advanced cancers
- Available in different strengths
- Comes as a tablet that's taken by mouth
Cons
- Common side effects include nausea, headache, breast tenderness
- Raises your risk of serious blood clots
- Taking the tablet in cycles can be hard to remember
- Not safe for people with liver problems
Common Side Effects for Menest
- Breast tenderness
- Nausea
- Headache
- Migraines
- Vomiting
- Stomach cramps
- Vaginal spotting/breakthrough bleeding
- Weight changes
Warnings for Menest
- Uterine (endometrial) cancer
- Breast cancer
- Blood clots and stroke
- Heart disease and heart attacks
- Dementia
- Gallbladder and liver problems
- Vision problems
- High triglycerides
- Low thyroid hormone levels (hypothyroidism)
- Fluid Retention
- Changes in calcium levels in the blood
- Worsening of other health conditions
Summary for Premarin
Premarin (conjugated estrogens) is an oral estrogen hormone tablet that's used to treat various conditions in adults. Most commonly, it relieves menopausal symptoms such as vaginal dryness and hot flashes. The medication is also used for treating low estrogen levels, certain advanced stages of breast or prostate cancers, and osteoporosis after menopause. Depending on what you're using it for, the medication can be taken daily or in cycles. Side effects include headache, stomach pain, nausea, and breast pain.
Indications for Premarin
- Hot flashes, night sweats, and flushes caused by menopause
- Vaginal dryness caused by menopause
- Low estrogen levels due to certain conditions
- Certain advanced stages of breast cancer
- Certain advanced stages of prostate cancer
- Prevention of bone loss (osteoporosis) after menopause
Pros and Cons for Premarin
Pros
- Relieves multiple menopausal symptoms
- Available in multiple strengths, allowing you to customize your dose
- Comes as a tablet that you take by mouth
Cons
- Raises your risk of certain cancers, blood clots, and strokes
- Some people might need to take it with another hormone called progestin
- Not a first-choice medication for treating bone loss after menopause
Common Side Effects for Premarin
- Headache (13-14%)
- Abnormal vaginal bleeding (2-13%)
- Breast pain (7-12%)
- Stomach pain (8-11%)
- Passing gas (4-6%)
- Vaginal discharge (4-5%)
- Back pain (3-5%)
- General pain (3-5%)
- Nausea (3-5%)
- Insomnia (3-5%)
- Depression (3-5%)
- Weakness (2-5%)
Warnings for Premarin
- Uterine (endometrial) cancer
- Breast cancer
- Blood clots and stroke
- Heart disease and heart attacks
- Dementia
- Gallbladder and liver problems
- Vision problems
- High triglycerides
- Low thyroid hormone levels (hypothyroidism)
- Fluid Retention
- Changes in calcium levels in the blood
- Worsening of other health conditions
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