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Menest vs. Premarin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Menest

(esterified estrogens)

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Premarin

 

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Summary for Menest

Prescription only

Menest (esterified estrogens) is an estrogen hormone replacement used to relieve menopause symptoms like hot flashes and vaginal dryness. It's also used to treat low estrogen levels and certain advanced prostate and breast cancers. The tablet is taken by mouth, and dosage depends on why you're taking it. Menest (esterified estrogens) is only available as a brand-name medication since there is no generic version. Potential side effects include breast tenderness, nausea, and headache.

Indications for Menest

Pros and Cons for Menest

Pros

  • Relieves multiple menopause symptoms
  • Also treats low estrogen conditions and certain advanced cancers
  • Available in different strengths
  • Comes as a tablet that's taken by mouth

Cons

  • Common side effects include nausea, headache, breast tenderness
  • Raises your risk of serious blood clots
  • Taking the tablet in cycles can be hard to remember
  • Not safe for people with liver problems

Common Side Effects for Menest

  • Breast tenderness
  • Nausea
  • Headache
  • Migraines
  • Vomiting
  • Stomach cramps
  • Vaginal spotting/breakthrough bleeding
  • Weight changes

Warnings for Menest

  • Uterine (endometrial) cancer
  • Breast cancer
  • Blood clots and stroke
  • Heart disease and heart attacks
  • Dementia
  • Gallbladder and liver problems
  • Vision problems
  • High triglycerides
  • Low thyroid hormone levels (hypothyroidism)
  • Fluid Retention
  • Changes in calcium levels in the blood
  • Worsening of other health conditions

Summary for Premarin

Prescription only

Premarin (conjugated estrogens) is an oral estrogen hormone tablet that's used to treat various conditions in adults. Most commonly, it relieves menopausal symptoms such as vaginal dryness and hot flashes. The medication is also used for treating low estrogen levels, certain advanced stages of breast or prostate cancers, and osteoporosis after menopause. Depending on what you're using it for, the medication can be taken daily or in cycles. Side effects include headache, stomach pain, nausea, and breast pain.

Indications for Premarin

Pros and Cons for Premarin

Pros

  • Relieves multiple menopausal symptoms
  • Available in multiple strengths, allowing you to customize your dose
  • Comes as a tablet that you take by mouth

Cons

  • Raises your risk of certain cancers, blood clots, and strokes
  • Some people might need to take it with another hormone called progestin
  • Not a first-choice medication for treating bone loss after menopause

Common Side Effects for Premarin

  • Headache (13-14%)
  • Abnormal vaginal bleeding (2-13%)
  • Breast pain (7-12%)
  • Stomach pain (8-11%)
  • Passing gas (4-6%)
  • Vaginal discharge (4-5%)
  • Back pain (3-5%)
  • General pain (3-5%)
  • Nausea (3-5%)
  • Insomnia (3-5%)
  • Depression (3-5%)
  • Weakness (2-5%)

Warnings for Premarin

  • Uterine (endometrial) cancer
  • Breast cancer
  • Blood clots and stroke
  • Heart disease and heart attacks
  • Dementia
  • Gallbladder and liver problems
  • Vision problems
  • High triglycerides
  • Low thyroid hormone levels (hypothyroidism)
  • Fluid Retention
  • Changes in calcium levels in the blood
  • Worsening of other health conditions

Prices with our coupons for Menest vs. Premarin

Price Card Drug Icon
Menest30 tablets / 0.625mg
$83.64$105.73
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Price Card Drug Icon
Premarin30 tablets / 0.625mg
$99.00$261.58
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