Menest
(esterified estrogens)
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Summary for Menest
Menest (esterified estrogens) is an estrogen hormone replacement used to relieve menopause symptoms like hot flashes and vaginal dryness. It's also used to treat low estrogen levels and certain advanced prostate and breast cancers. The tablet is taken by mouth, and dosage depends on why you're taking it. Menest (esterified estrogens) is only available as a brand-name medication since there is no generic version. Potential side effects include breast tenderness, nausea, and headache.
Indications for Menest
- Hot flashes, night sweats, and flushes from menopause
- Vaginal dryness and irritation from menopause
- Low estrogen from hypogonadism
- Low estrogen from castration (removal of the ovaries)
- Primary ovarian failure (ovaries stop working before age 40)
- Certain advanced breast cancers
- Certain advanced advanced prostate cancers
Pros and Cons for Menest
Pros
- Relieves multiple menopause symptoms
- Also treats low estrogen conditions and certain advanced cancers
- Available in different strengths
- Comes as a tablet that's taken by mouth
Cons
- Common side effects include nausea, headache, breast tenderness
- Raises your risk of serious blood clots
- Taking the tablet in cycles can be hard to remember
- Not safe for people with liver problems
Common Side Effects for Menest
- Breast tenderness
- Nausea
- Headache
- Migraines
- Vomiting
- Stomach cramps
- Vaginal spotting/breakthrough bleeding
- Weight changes
Warnings for Menest
- Uterine (endometrial) cancer
- Breast cancer
- Blood clots and stroke
- Heart disease and heart attacks
- Dementia
- Gallbladder and liver problems
- Vision problems
- High triglycerides
- Low thyroid hormone levels (hypothyroidism)
- Fluid Retention
- Changes in calcium levels in the blood
- Worsening of other health conditions
Summary for Premarin
Premarin (conjugated estrogens) oral tablet is an estrogen hormone replacement therapy (HRT) used to treat menopause symptoms, such as hot flashes and vaginal dryness, and other conditions caused by low estrogen levels. It can also help prevent osteoporosis after menopause and treat certain advanced breast or prostate cancers. Depending on why you're taking it, you might take it by mouth every day or in cycles. Common side effects include headache, stomach pain, nausea, and breast pain.
Indications for Premarin
- Hot flashes, night sweats, and flushes caused by menopause
- Vaginal dryness caused by menopause
- Low estrogen levels due to certain conditions
- Advanced breast cancer
- Advanced prostate cancer
- Prevention of bone loss (osteoporosis) after menopause
Pros and Cons for Premarin
Pros
- Relieves multiple menopause symptoms
- Available in multiple strengths
- Comes as a tablet that you take by mouth
Cons
- Raises your risk of blood clots, stroke, and certain cancers
- Some people might need to take it with another hormone called progestin
- Can cause vaginal bleeding and spotting
Common Side Effects for Premarin
- Headache (13-14%)
- Abnormal vaginal bleeding (2-13%)
- Breast pain (7-12%)
- Stomach pain (8-11%)
- Passing gas (4-6%)
- Vaginal discharge (4-5%)
- Back pain (3-5%)
- General pain (3-5%)
- Nausea (3-5%)
- Insomnia (3-5%)
- Depression (3-5%)
- Weakness (2-5%)
Warnings for Premarin
- Blood clots, heart attacks, and strokes
- Uterine (endometrial) cancer
- Breast cancer
- Dementia
- Ovarian cancer
- Liver or gallbladder problems
- Changes in calcium levels in the blood
- Vision problems
- High triglycerides (fat) levels
- Low thyroid hormone levels
- Buildup of fluids in your body (fluid retention)
- Worsening of certain other health conditions
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