Compare Korlym vs. Mifepristone
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Korlym (mifepristone)Mifepristone (Mifeprex)
- Korlym (mifepristone)Mifepristone (Mifeprex)
Summary of Korlym vs. Mifepristone
Summary for Cortisol receptor blockerPrescription onlyKorlym, also known by its generic name mifepristone, is a cortisol receptor blocker. It's used to manage high blood sugar levels in certain adults with Cushing's syndrome who have Type 2 diabetes. This medication is an option for people if they can't have surgery or if surgery didn't help with their condition. Korlym (mifepristone) is a tablet that's taken by mouth once per day with food. Dosage adjustments are based on how well the medication is working. It also depends on whether you have unpleasant side effects. Common side effects include nausea, fatigue, and headache.
Summary for AntiprogestinPrescription onlyMifepristone (Mifeprex) is used together with misoprostol (Cytotec) for medical abortion (using prescribed medications to end a pregnancy). These medications are typically used in people no more than 10 weeks pregnant. In some cases, it can be prescribed to people up to 11 weeks pregnant. Mifepristone (Mifeprex) is only available by prescription in certain U.S. states from certain healthcare providers (including some pharmacies). Taking mifepristone (Mifeprex) with misoprostol (Cytotec) can cause side effects like nausea and cramps. Vaginal bleeding is also an expected symptom after you've taken these abortion pills, but a lot of heavy bleeding can be a sign of serious complications. You'll need to follow up with your provider to make sure your pregnancy has ended completely.
Indications of Korlym vs. Mifepristone
Indications for•Managing high blood sugar levels in adults with Cushing's syndrome and Type 2 diabetes who can't have surgery or who've already tried surgeryIndications for•Ending a pregnancy that's no more than 10 weeks along, when used together with misoprostol (Cytotec)Pros and Cons of Korlym vs. Mifepristone
Pros and Const for Cortisol receptor blockerPros•A possible option for people with Cushing's syndrome who can't have surgery or who've had surgery without success•Taken by mouth just once per dayCons•Not reliable to monitor cortisol levels during treatment•Not safe for people who are pregnantPros and Const for AntiprogestinPros•No surgery required to end pregnancy•Between 93% and 98% effective at ending pregnancy through 10 weeks•Might be more affordable than a surgery to end pregnancy•Can safely take at home under the care of a certified healthcare providerCons•Requires close contact with your healthcare provider to make sure the medication worked•Commonly causes cramps, vaginal bleeding, and nausea•Risk of serious bleeding or infections•Can't take if you have an ectopic pregnancyCommon Side Effects of Korlym vs. Mifepristone
Common Side Effects for•Nausea (48%)•Fatigue (48%)•Headache (44%)•Low potassium levels (34%)•Joint pain (30%)•Vomiting (26%)•Swelling in the hands, ankles, or feet (26%)•High blood pressure (24%)•Dizziness (22%)•Low appetite (20%)•Dry mouth (18%)Common Side Effects for•Nausea (51-75%)•Weakness (55-58%)•Fever or chills (48%)•Vomiting (37-48%)•Headache (41-44%)•Diarrhea (18-43%)•Dizziness (39-41%)Warnings of Korlym vs. Mifepristone
Common Side Effects for•Loss of pregnancy•Must use nonhormonal birth control if you're sexually active and able to get pregnant•Low adrenal hormone levels (adrenal insufficiency)•Vaginal bleeding and changes to the uterine lining•Low potassium levels•Life-threatening abnormal heart rhythm (QT prolongation)•Interactions with other medicationsCommon Side Effects for•Serious infection•Serious vaginal bleedingPrices with our coupons for Korlym vs. Mifepristone
Browse medications
View AllResearch prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.