Indacaterol vs. Perforomist for COPD: Important Differences and Potential Risks.

Key takeaways

Indacaterol (Arcapta Neohaler) and formoterol (Perforomist) are both long-acting beta-agonists (LABAs) used to treat chronic obstructive pulmonary disease (COPD). However, they have several differences. Indacaterol was available as an inhaler but has been discontinued and is no longer available in the U.S., while formoterol is available by prescription and requires a nebulizer for administration. Formoterol is typically dosed at 20 micrograms twice daily using a nebulizer. Common side effects of formoterol include diarrhea, nausea, and dizziness, and it should not be used for asthma or sudden breathing problems. Additionally, using formoterol with albuterol may increase the risk of heart-related side effects.

Arcapta Neohaler

(indacaterol)

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Formoterol

(Perforomist)

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Summary for Indacaterol

Discontinued

Arcapta Neohaler (indacaterol) controls your chronic obstructive pulmonary disease (COPD) and helps you breathe easier. It is no longer available and has been replaced by newer inhalers.

Pros and Cons for Indacaterol

Pros

Cons

Summary for Perforomist

Prescription only

Formoterol (Perforomist) is good for long-term control of chronic obstructive pulmonary disease (COPD) symptoms but it requires a nebulizer machine.

Indications for Perforomist

Chronic obstructive pulmonary disease (COPD)

Pros and Cons for Perforomist

Pros

Works well to control chronic obstructive pulmonary disease (COPD)
Starts working in as little as 5 minutes
Using a jet nebulizer is easier to use than a handheld inhaler, especially for older adults
Can be used in people who are pregnant and/or breastfeeding, but discuss with your healthcare provider because there might be better options for you

Cons

A nebulizer machine is more expensive than inhalers and there isn't a generic version
Takes about 5 to 10 minutes to use in the morning and in the evening
Doesn't work fast enough to relieve sudden breathing problems like other fast-acting or rescue inhalers, such as albuterol (ProAir)
Not used to treat asthma