Skip to main content

Compare
Plendil vs. Dynacirc

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Felodipine ER (Plendil) and isradipine (Dynacirc) are both calcium channel blockers used to treat high blood pressure. Felodipine ER is typically taken once daily as a tablet, while isradipine is usually taken twice daily as a capsule. Felodipine ER is available as a lower-cost generic, but the brand name Plendil has been discontinued. Similarly, the brand name Dynacirc for isradipine is no longer available, but the generic form is still on the market. Common side effects for both medications include swelling, headache, and dizziness. Both medications can be taken with or without food, but it's important to be consistent with how you take it. Both medications require careful monitoring of blood pressure and have specific instructions regarding missed doses and potential interactions with other medications.

Felodipine ER

(Plendil)

Get free coupons

Isradipine

 

Get free coupons

Summary for Plendil

Prescription only

Felodipine ER (Plendil) is a calcium channel blocker. It lowers blood pressure by relaxing your blood vessels. This medication is one of the first-choice options for treating high blood pressure in adults. It's taken by mouth, typically once daily. Some side effects of this medication include swelling, headache, and flushing. Brand name Plendil has been discontinued.

Indications for Plendil

Pros and Cons for Plendil

Pros

  • Taken by mouth
  • Taken once daily
  • Available as a lower-cost generic medication

Cons

  • Only available as a tablet
  • Not a good choice if you've heart failure
  • Not recommended in pregnancy

Common Side Effects for Plendil

  • Swelling in the arms, hands, legs, or feet (up to 17%)
  • Headache (up to 15%)
  • Flushing (up to 7%)

Warnings for Plendil

  • Severely low blood pressure
  • Caution with heart failure
  • Swelling

Summary for Dynacirc

Prescription only

Isradipine is used to lower blood pressure. The long-acting version and the brand name version of isradipine have been discontinued. But the generic is still available as a capsule that's taken by mouth, typically twice daily. Like all calcium channel blockers, some common side effects of isradipine include swelling, dizziness, and headache.

Indications for Dynacirc

  • High blood pressure (hypertension)

Pros and Cons for Dynacirc

Pros

  • Lowers risk of heart attack and stroke caused by high blood pressure
  • Can be used in combination with a thiazide-type water pill like hydrochlorothiazide
  • Taken by mouth

Cons

  • Can cause headache and swelling in the legs and feet
  • Typically taken twice daily
  • Only available as a capsule

Common Side Effects for Dynacirc

  • Headache (14%)
  • Swelling in the legs, feet, or hands (7%)
  • Dizziness (7%)

Warnings for Dynacirc

  • Low blood pressure
  • Risk of worsening heart failure

Prices with our coupons for Plendil vs. Dynacirc

Price Card Drug Icon
Felodipine ER90 tablets / 10mg
$24.90$148.60
Get free coupons
More Information
Price Card Drug Icon
Isradipine180 capsules / 5mg
$188.44$1,064.58
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.