Danziten vs. Tasigna for Leukemia: Important Differences and Potential Risks.

Danziten

(nilotinib)

Tasigna

(nilotinib)

Summary for Danziten

Prescription only

Danziten (nilotinib) is an oral medication used to treat adults with Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), a type of blood cancer. It's FDA approved for people who are newly diagnosed or who have previously received treatment with imatinib. The medication comes as a tablet that's taken by mouth twice a day, about 12 hours apart, with or without food. Common side effects include rash, nausea, and headache.

Indications for Danziten

Newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in adults
Ph+ CML in adults when imatinib no longer works or causes side effects that are too difficult to tolerate

Pros and Cons for Danziten

Pros

Can be taken with or without food
Tablet taken by mouth
Option if imatinib doesn't work or causes bothersome side effects

Cons

Risk of dangerous heart rhythm changes
Requires frequent labs and monitoring
Interactions with many medications

Common Side Effects for Danziten

Newly diagnosed Ph+ CML

Rash (38%)
Headache (32%)
Common cold symptoms (27%)
Tiredness (23%)
Nausea (22%)
Joint pain (22%)
Itching (21%)
Constipation (20%)

Ph+ CML after previous treatment

Nausea (22-37%)
Rash (29-36%)
Headache (20-35%)
Tiredness (23-32%)
Itching (20-32%)
Vomiting (13-29%)
Diarrhea (24-28%)
Fever (22-28%)
Cough (18-27%)
Night sweats (12-27%)
Constipation (19-26%)
Joint pain (16-26%)
Common cold symptoms (15-24%)
Pain in the arms and legs (18-20%)

Warnings for Danziten

Heart rhythm changes and sudden deaths
Low blood cell counts
Heart and blood vessel blockages
Inflammation of the pancreas
Liver problems
Tumor lysis syndrome
Bleeding
Fluid buildup
Slowed growth in children
Harm to unborn baby

Summary for Tasigna

Prescription only

Tasigna (nilotinib) is an oral medication used to treat a certain type of chronic myelogenous leukemia (CML). It’s a type of targeted anticancer treatment. Tasigna (nilotinib) is one of the recommended options for CML in adults and children. But, it’s taken twice a day and can’t be taken with food, so it can be hard to schedule around your meals.

Indications for Tasigna

Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML)

Pros and Cons for Tasigna

Pros

Recommended treatment option for CML in certain adults
Can be used in children
More precise in the way it targets cancer cells, compared to traditional chemotherapy

Cons

Can’t be taken around the time you eat food
Requires regular blood tests so your provider can monitor for side effects
Available as brand only, so can be expensive
Contains lactose, so might not be a good option for people who are lactose intolerant or have problems absorbing certain sugars

Common Side Effects for Tasigna

Rash (up to 38%)
Nausea (up to 37%)
Headache (up to 35%)
Tiredness (up to 32%)
Itchy skin (up to 32%)
Vomiting (up to 29%)
Diarrhea (up to 28%)
Fever (up to 28%)
Cold-like symptoms (up to 27%)
Cough (up to 27%)
Sweating at night (up to 27%)
Constipation (up to 26%)
Joint pain (up to 26%)
Pain in arms or legs (up to 20%)

^{*Side effects listed were reported in adults. Side effects in children might differ. Please see source for more details.}

Warnings for Tasigna

Changes in heart rhythm
Blood flow problems, heart attack, or stroke
Low blood counts
Pancreatitis (inflammation of the pancreas)
Liver problems
Fluid buildup or swelling in the body
Bleeding
Tumor lysis syndrome
Growth problems in children
Harm to unborn baby

Prices with our coupons for Danziten vs. Tasigna

Danziten112 tablets / 71mg of

$17,310.25$19,652.23

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Nilotinib1 bottle / 120 capsules of 50mg

$6,615.64$17,957.52

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Danziten vs. Tasigna

Danziten

Tasigna

Summary for Danziten

Indications for Danziten

Pros and Cons for Danziten

Pros

Cons

Common Side Effects for Danziten

Warnings for Danziten

Summary for Tasigna

Indications for Tasigna

Pros and Cons for Tasigna

Pros

Cons

Common Side Effects for Tasigna

Warnings for Tasigna

Prices with our coupons for Danziten vs. Tasigna

Browse medications by letter

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Danziten

Tasigna

Summary for Danziten

Indications for Danziten

Pros and Cons for Danziten

Pros

Cons

Common Side Effects for Danziten

Warnings for Danziten

Summary for Tasigna

Indications for Tasigna

Pros and Cons for Tasigna

Pros

Cons

Common Side Effects for Tasigna

Warnings for Tasigna