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Clotrimazole non-prescription vs. Miconazole

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Clotrimazole

 

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Miconazole

(Monistat)

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Summary for Clotrimazole non-prescription

Over-the-counter

Clotrimazole is an antifungal cream that's placed inside the vagina or onto the surrounding skin. It's used to treat vaginal yeast infections. This medication also helps relieve related symptoms, like itching, burning, and discomfort. Clotrimazole vaginal cream comes in 3-day and 7-day treatment courses, both of which are available over the counter as a lower-cost generic medication. Possible side effects of this vaginal cream include vaginal irritation, itching, and burning.

Indications for Clotrimazole non-prescription

Pros and Cons for Clotrimazole non-prescription

Pros

  • Can treat most vaginal yeast infections in 3 or 7 days, depending on the strength of the cream you have
  • Only need to use once a day (for treating vaginal yeast infection)
  • Available over the counter as a lower-cost generic

Cons

  • Can leak out after inserting into the vagina, which can be messy or cause discomfort
  • Can cause vaginal burning or irritation
  • Not recommended to have vaginal sex during treatment

Common Side Effects for Clotrimazole non-prescription

  • Burning feeling in the vagina or in the area around the opening of the vagina (less than 10%)

Warnings for Clotrimazole non-prescription

  • Might not be appropriate for undiagnosed vaginal symptoms
  • Contact a healthcare professional for frequent or severe vaginal symptoms

Summary for Miconazole

Over-the-counter

Miconazole (Monistat) is used to treat a vaginal yeast infection in adults and children 12 years and older. It's available over the counter as vaginal creams, inserts/suppositories, or combination kits. The entire treatment lasts 1, 3, or 7 days, depending on the product. Common side effects include mild vaginal burning, irritation, and itching.

Indications for Miconazole

Pros and Cons for Miconazole

Pros

  • Available over the counter
  • Many treatment options (1, 3, or 7 days)
  • Targets infection directly at the site

Cons

  • Can cause vaginal burning, itching, or irritation
  • Might be messy or cause leakage
  • Requires vaginal insertion

Common Side Effects for Miconazole

Warnings for Miconazole

  • Damage to condoms and diaphragms
  • Symptoms don't go away

Prices with our coupons for Clotrimazole non-prescription vs. Miconazole

Price Card Drug Icon
Clotrimazole Non-Prescription1 tube / 45g of 1%
$15.40-
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Price Card Drug Icon
Miconazole30 tubes / 2%
$11.34-
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