Agamree vs. Deflazacort for Muscular Dystrophy: Important Differences and Potential Risks.

Agamree

(vamorolone)

Emflaza

(deflazacort)

Summary for Agamree

Prescription only

Agamree (vamorolone) is a corticosteroid. It's FDA approved to treat Duchenne muscular dystrophy (DMD) in people 2 years and older. The medication helps with muscle weakness and movement problems from this genetic condition. Agamree (vamorolone) is a liquid medication that you take by mouth, usually once a day. Your specific dosage depends on your weight. Some side effects can include mood changes, trouble sleeping, and a bigger appetite.

Indications for Agamree

Duchenne muscular dystrophy (DMD)

Pros and Cons for Agamree

Pros

Taken once daily
Comes as a liquid
Comes with oral syringes and vial adapters for easy administration
Less likely to cause bone loss and stunted growth than prednisone

Cons

Only available in an orange flavor, so not ideal for people who don’t like the taste of orange
Should take with food, which can be inconvenient
Can cause mood swings or sleep problems
Risk of withdrawal symptoms if you stop taking the medication suddenly

Common Side Effects for Agamree

Rounder face, stretch marks, and other symptoms of Cushing syndrome (up to 29%)
Changes in mood, sleep, or behavior (up to 21%)
Vomiting (up to 17%)
Weight gain (up to 11%)
Low vitamin D levels (up to 11%)

Warnings for Agamree

Greater risk of infections
Caution use with vaccines
Mood and behavior changes
Weakened bones
High blood pressure
Kidney problems or worsening heart failure
Eye problems with long-term use
Stomach damage
Muscle pain in people with nerve issues
Risk of blood clots
Possible risk of rare cancer
Withdrawal
Pheochromocytoma crisis

Summary for Deflazacort

Prescription only

Emflaza (deflazacort) is a medication taken once daily to treat a rare, genetic problem called Duchenne muscular dystrophy (DMD). DMD is usually seen in children, and it's known to cause muscle damage and weakness. Emflaza (deflazacort) can be taken by children as young as 2 years old, but this medication can cause a lot of side effects.

Indications for Deflazacort

Duchenne muscular dystrophy (DMD) in people 2 years and older

Pros and Cons for Deflazacort

Pros

Available in tablets and liquid suspension
Tablets can be crushed if needed
Available in multiple different strengths
Only needs to be taken once a day

Cons

Can cause many problems with hormones and growth development
Can be harmful if taken during pregnancy or breastfeeding
Might take a long time to notice an improvement in symptoms

Common Side Effects for Deflazacort

Cushingoid appearance (facial puffiness) (33%)
Weight gain (20%)
Higher appetite (14%)
Upper respiratory tract infection (i.e., common cold, 12%)
Cough (12%)
Frequent urination (12%)
Nose or throat infection (10%)
Excessive hair growth (10%)
Obesity (10%)
Redness (8%)
Irritability (8%)
Runny nose (8%)
Stomach discomfort (6%)

Warnings for Deflazacort

Changes to hormone levels
High blood sugar
Risk of infections
Changes in heart and kidney function
Stomach problems
Changes in mood and behavior
Bone and growth problems
Vision problems
Serious skin rashes
Cancer
Nerve problems
Harm to unborn babies and infants
Blood clots

Prices with our coupons for Agamree vs. Deflazacort

Agamree1 kit / 100ml of 40mg/ml

$10,446.81$11,636.57

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Deflazacort30 tablets / 30mg

$3,597.75-

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Agamree vs. Deflazacort

Agamree

Emflaza

Summary for Agamree

Indications for Agamree

Pros and Cons for Agamree

Pros

Cons

Common Side Effects for Agamree

Warnings for Agamree

Summary for Deflazacort

Indications for Deflazacort

Pros and Cons for Deflazacort

Pros

Cons

Common Side Effects for Deflazacort

Warnings for Deflazacort

Prices with our coupons for Agamree vs. Deflazacort

Browse medications by letter

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Agamree

Emflaza

Summary for Agamree

Indications for Agamree

Pros and Cons for Agamree

Pros

Cons

Common Side Effects for Agamree

Warnings for Agamree

Summary for Deflazacort

Indications for Deflazacort

Pros and Cons for Deflazacort

Pros

Cons

Common Side Effects for Deflazacort

Warnings for Deflazacort