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Adzenys XR-ODT vs. Vyvanse

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Adzenys XR-ODT

(amphetamine)

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Vyvanse

(lisdexamfetamine)

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Summary for Adzenys XR-ODT

Prescription only

Adzenys XR-ODT (amphetamine) is a stimulant medication. It helps treat attention deficit-hyperactivity disorder (ADHD) in adults and children 6 years and older. It comes as an orally disintegrating tablet (ODT). This means that it dissolves quickly when it's placed on the tongue. You take the medication once a day in the morning. Your prescriber can adjust the dosage based on how well it's working and what side effects you might have. Possible side effects include trouble sleeping, loss of appetite, and high blood pressure. Adzenys XR-ODT (amphetamine) is a brand-name medication; there's no generic version yet.

Indications for Adzenys XR-ODT

Pros and Cons for Adzenys XR-ODT

Pros

  • Taken once a day
  • Good option for people who can't swallow pills whole
  • Can help you pay attention for up to 12 hours

Cons

  • Is a controlled substance, so there are special requirements to get it filled
  • Must take gradually lower doses to stop the medication to avoid withdrawal symptoms
  • Can cause higher blood pressure

Common Side Effects for Adzenys XR-ODT

Children 6 to 12 years old:

Children 13 to 17 years old:

  • Low appetite (36%)
  • Trouble sleeping (12%)
  • Stomach pain (11%)
  • Weight loss (9%)

Adults:

  • Dry mouth (35%)
  • Low appetite (33%)
  • Trouble sleeping (27%)
  • Headache (26%)
  • Weight loss (10%)

Warnings for Adzenys XR-ODT

  • Risk of misuse and addiction
  • Risks to people with serious heart conditions
  • Higher blood pressure and faster heart rate
  • Strange thoughts or behaviors
  • Slow growth in children
  • Problems with blood flow in the arms and legs, including Raynaud's phenomenon
  • Serotonin syndrome

Summary for Vyvanse

Prescription only

Vyvanse, the brand name for lisdexamfetamine, is a stimulant medication. It's used to treat attention deficit-hyperactivity disorder (ADHD) in people 6 years and older. It can also treat binge eating disorder (BED) in adults. Vyvanse (lisdexamfetamine) comes as capsules and chewable tablets. It's taken once per day in the morning. The dosage starts low and gets adjusted based on how you respond to the medication. Common side effects include trouble sleeping and loss of appetite. Vyvanse (lisdexamfetamine) is a controlled substance because it has a high risk of misuse and dependency.

Indications for Vyvanse

Pros and Cons for Vyvanse

Pros

  • A first-choice ADHD medication
  • Can help with ADHD for up to 14 hours with each dose
  • For binge eating disorder, can lower the number of binge-eating days per week by about one and a half days
  • Has a few options for people who have trouble swallowing pills whole (open the capsule or switch to chewable tablets)

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Might need to take gradually lower doses before stopping to avoid withdrawal symptoms
  • Not the best choice for people with heart conditions

Common Side Effects for Vyvanse

ADHD

Binge eating disorder

  • Dry mouth (36%)
  • Trouble sleeping (20%)

Warnings for Vyvanse

  • Risk of misuse and addiction
  • Risks to people with serious heart problems
  • Higher blood pressure and faster heart rate
  • Strange thoughts or behavior
  • Slow growth in children
  • Problems with blood flow in the arms and legs, including Raynaud's phenomenon
  • Serotonin syndrome

Prices with our coupons for Adzenys XR-ODT vs. Vyvanse

Price Card Drug Icon
Amphetamine ER30 orally disintegrating tabs / 18.8mg
$170.99$686.53
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Price Card Drug Icon
Lisdexamfetamine30 capsules / 30mg
$67.98$389.28
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