colistimethate

Colistimethate (Coly-Mycin M) is used for the treatment of a variety of infections caused by Klebsiella aerogenes, Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa. These bacteria can cause infections in many parts of the body, such as the bladder, blood, skin, and lungs.

Colistimethate (Coly-Mycin M) is an older antibiotic that isn't as commonly used today because it can seriously damage your kidneys and also cause nervous system problems. It's most often used in people who have certain resistant bacteria (bacteria that's difficult to fight off, even with the use of many antibiotics). Although less common, colistimethate (Coly-Mycin M) can be considered an empiric antibiotic. Empiric therapy means it's used to treat several bacteria before it's known which specific bacteria is causing the infection.

Colistimethate (Coly-Mycin M) is an antibiotic that kills bacteria by destroying the protective covering around them.

Colistimethate (Coly-Mycin M) is given as an injection through the veins or into the muscle. It's typically given to people in the hospital by a healthcare provider. But, depending on the infection, some people might be able to take colistimethate (Coly-Mycin M) at home under instructions from their provider.

Dosing for colistimethate (Coly-Mycin M) will depend on your weight, how healthy your kidneys are, and the severity of your infection. In general, the typical dose of colistimethate (Coly-Mycin M) for adults and children is 2.5 to 5 mg/kg per day, which is split up 2 to 4 times per day and injected into the vein or muscle. Your dose might be lower or less frequent if you have kidney problems.