Skip to main content

Vaptans

Vaptans, or vasopressin receptor antagonists, are used to treat hyponatremia, or abnomally low levels of sodium in the blood. Vaptans can also slow the progression of certain kidney diseases. They work by inhibiting the effect of vasopressin in the body. Vasopressin is a hormone that helps regulate the body's water retention, blood pressure, blood sodium levels, and kidney function.

Why are vaptans prescribed?

  1. Hyponatremia (100%)
  2. Kidney Disease (0%)

Key takeaways

Vaptans are used to treat low blood sodium levels and autosomal dominant polycystic kidney disease (ADPKD). They work by blocking the action of vasopressin, a hormone that regulates water balance in your body, which helps to increase the amount of water excreted in your urine and raise your blood sodium levels. These medications are available in oral forms. Examples include tolvaptan (Samsca, Jynarque). You can choose the form that best fits your needs.

Prices for popular Vaptans medications
Viewing 2 of 2 medications
tablet icon

Samsca (tolvaptan (samsca))

TOLVAPTAN treats low sodium levels in your body. It works by helping your kidneys remove more fluid from your blood through the urine without losing too much sodium. This helps your body maintain the right amount of sodium it needs.
See pricesMore info
carton icon

Jynarque (tolvaptan (jynarque))

Jyrnarque is a used to slow kidney function decline in adults who are at risk for rapidly progressing autosomal dominant polycystic kidney disease. There are currently no generic alternatives to Jynarque. It is covered by most Medicare and insurance plans.
See pricesMore info
Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

Subscribe and save

Get prescription saving tips and more from GoodRx Health. Enter your email to sign up

By providing your email, you consent to receive marketing communications from GoodRx, which may include content and/or data related to men's health, women's health, reproductive care, or sexual health. You agree to the GoodRx Terms of Use and acknowledge the Privacy Policy. You can unsubscribe at any time.

Browse medications

View All
Research prescriptions and over-the-counter medications from A to Z, compare drug prices, and start saving.
ABCDFGHIJKLMNOPQRSTUVWXYZ