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Tryptophan Hydroxylase Inhibitor

Tryptophan hydroxylase inhibitors are used for the treatment of carcinoid syndrome diarrhea. They work by decreasing the production of peripheral serotonin, and therefore the frequency of diarrhea.

Why are tryptophan hydroxylase inhibitor prescribed?

  1. Diarrhea (100%)

Key takeaways

Tryptophan hydroxylase inhibitors are used to treat carcinoid syndrome diarrhea. These medications work by blocking the enzyme tryptophan hydroxylase. It reduces the production of serotonin, a chemical that's involved in regulating gut health. Tryptophan hydroxylase inhibitors are available in oral forms. An example includes Xermelo (telotristat). You can take these medications as prescribed to help manage your condition effectively.

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Xermelo

Xermelo (telotristat ethyl) is an expensive drug used to treat carcinoid syndrome diarrhea in combination with somatostatin analog (SSA) therapy. This drug is indicated for adults inadequately controlled by SSA therapy. There are currently no generic alternatives for Xermelo.
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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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