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Tadalafil (Cialis) Coupon - Tadalafil (Cialis) 5mg tablet

tadalafil

Generic Cialis
Used for Erectile Dysfunction, Benign Prostatic Hyperplasia
Used for Erectile Dysfunction, Benign Prostatic Hyperplasia

Tadalafil (Cialis) is taken by mouth either as needed before sexual activity or once daily for erectile dysfunction (ED). It's also taken once daily to treat symptoms from an enlarged prostate (benign prostatic hyperplasia, or BPH). Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include headache and indigestion. Tadalafil (Cialis) does interact with some medications, such as heart and blood pressure medications, and taking them together could lead to very low blood pressure and dizziness.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Connie Zheng, PharmD
Last reviewed on April 11, 2023
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageReviewsInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
basics-icon

What is Tadalafil (Cialis)?

What is Tadalafil (Cialis) used for?

  • Erectile dysfunction

  • Benign prostatic hyperplasia (BPH)

How Tadalafil (Cialis) works

Tadalafil (Cialis) is a phosphodiesterase-5 enzyme (PDE-5) inhibitor. It works by blocking PDE-5. This is a protein in your body that breaks down the molecules that normally cause an erection. When it blocks PDE-5, tadalafil (Cialis) helps an erection occur by allowing certain muscles in the penis to relax and the penis to fill with blood.

While it's not fully clear how tadalafil (Cialis) helps treat symptoms of BPH, researchers think it helps relax the muscles in the prostate (a small gland in the groin).

Are you looking for information on Adcirca (tadalafil) instead?
When does Tadalafil (Cialis) start working?
Time passed since treatment started:
MINUTES
HOURS
DAYS
WEEKS
MONTHS
Initial effect
Full effect

Drug Facts

Common BrandsCialis
Drug ClassPDE-5 inhibitor
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only

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basics-icon

What are the side effects of Tadalafil (Cialis)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Once-daily use of tadalafil (Cialis) (for ED or BPH):
  • Headache (3-6%)
  • Runny nose, sore throat, and other symptoms of the common cold (3-6%)
  • Indigestion (4-5%)
  • Stomach upset (3-5%)
  • Back pain (3%)
As-needed use of tadalafil (Cialis) (for ED):
  • Headache (11-15%)
  • Indigestion (4-10%)
  • Back pain (3-6%)

Other Side Effects

  • Muscle ache
  • Flushing
  • Pain in arms or legs
  • Diarrhea
  • Dizziness

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Erection lasting for more than 4 hours
  • Vision loss
  • Dangerously low blood pressure: feeling faint or weak, dizziness, blurry vision, feeling confused
When do Tadalafil (Cialis) possible side effects begin and end?
Time passed since treatment started:
HOURS
DAYS
WEEKS
MONTHS
Headache
Stomach upset
Back pain
Muscle aches
Priapism
Seek immediate medical care if you experience this side effect.

Source: DailyMed

More on Tadalafil (Cialis) side effects

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6 Cialis Side Effects You Should Know About

Written by Daphne Berryhill, RPh

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Arm, back, or jaw pain

blurred vision

chest pain, discomfort, tightness, or heaviness

chills

cold sweats

confusion

dizziness

fainting

faintness or lightheadedness when getting up suddenly from a lying or sitting position

fast or irregular heartbeat

headache

hearing loss

increased erection

nausea

nervousness

pain or discomfort in the arms, jaw, back, or neck

pounding in the ears

slow or fast heartbeat

spontaneous penile erection

sweating

unusual tiredness or weakness

vomiting

Rare

Painful or prolonged erection of the penis

Incidence not known

Blindness

blistering, peeling, or loosening of the skin

cough

cracks in the skin

decrease or change in vision

diarrhea

difficulty with speaking

double vision

fast, irregular, pounding, or racing heartbeat or pulse

headache, severe and throbbing

hives or welts, itching, skin rash

inability to move the arms, legs, or facial muscles

inability to speak

joint or muscle pain

loss of heat from the body

numbness or tingling of the face, hands, or feet

red skin lesions, often with a purple center

red, irritated eyes

red, swollen skin

redness of the skin

redness or soreness of the eyes

scaly skin

slow speech

sores, ulcers, or white spots in the mouth or on the lips

stomach pain

sudden cardiac death

swelling of the feet or lower legs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Belching

heartburn

indigestion

stomach discomfort, upset, or pain

Less common

Bloody nose

body aches or pain

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

burning, dry, or itching eyes

burning feeling in the chest or stomach

congestion

difficulty with moving

difficulty with swallowing

dry mouth

dryness or soreness of the throat

excessive eye discharge

eye pain

feeling of constant movement of self or surroundings

feeling of warmth, redness of the face, neck, arms and occasionally, upper chest

fever

hoarseness

lack or loss of strength

loose stools

muscle aching, cramping, or stiffness

neck pain

pain in the arms or legs

pain or burning in the throat

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

reduced sensitivity to touch

runny or stuffy nose

sensation of spinning

sleepiness or unusual drowsiness

stomach upset

swelling of the eyelids

swelling or puffiness of the eyes or face

swollen joints

tearing

tender, swollen glands in the neck

tenderness in the stomach area

trouble with sleeping

upper stomach pain

voice changes

watering of the eyes

Rare

Changes in color vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Tadalafil (Cialis)

thumbs-up

Pros

One of the first-choice medications for treating ED

Can be taken either as needed or on a regular basis for those who need it more regularly

Lasts longer than other medications taken for ED

Can treat ED and BPH at the same time

Available as a lower-cost generic

thumbs-down

Cons

Not recommended if you've had a heart attack in the past 3 months, or a stroke or heart failure in the past 6 months

Can't be used if you've recently taken nitrates like isosorbide mononitrate (Monoket) or nitroglycerin (Nitrostat)

Takes longer to work compared to some other medications for ED

Can cause side effects like headache, stomach upset, and back pain

pharmacist-tips

Pharmacist tips for Tadalafil (Cialis)

pharmacist

  • Tadalafil (Cialis) can be taken with or without food, since food doesn't affect how well the medication works. Don't split the tablets, since the entire dose should be taken.

    • If you're taking tadalafil (Cialis) daily, take it at the same time every day for it to work best for you.

      • Don't take more than one dose of tadalafil (Cialis) unless instructed by your provider. Doing so could lead to more side effects like low blood pressure, dizziness, and vision problems.

        • If you get muscle or back pain with tadalafil (Cialis), it should get better in about 2 days. Talk to your provider if your symptoms don't improve.

          • If you have an erection for more than 4 hours, go to the emergency department right away as this can lead to damage to the penis.

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            faqs

            Frequently asked questions about Tadalafil (Cialis)

            How long does tadalafil (Cialis) take to work?
            If you're taking tadalafil (Cialis) for ED, you need to take this medication 30 minutes before sexual activity. But it might take 1-2 hours for the full effects of this medication to kick in. But if the as-needed dosing isn't working for you, talk with your provider about whether you can take a lower dose of tadalafil (Cialis) daily instead. Taking tadalafil (Cialis) daily might allow for more spontaneity because you don't have to time the dose before sexual activity. If you're taking tadalafil (Cialis) for BPH, you'll typically notice your symptoms improving within 1 to 2 weeks of starting this medication.
            How long does tadalafil (Cialis) last?
            Tadalafil (Cialis) can work for up to 36 hours after you take it. But this doesn't mean that the erection will last the entire time. It just means that you might be able to achieve more than one erection within this time frame without having to take another dose of tadalafil (Cialis). But if an erection lasts for longer than 4 hours, seek emergency medical care as this can lead to permanent damage to the penis.
            How much tadalafil (Cialis) can I take in a day?
            Take tadalafil (Cialis) as prescribed by your provider. If you're taking tadalafil (Cialis) as-needed for ED, you should take no more than one dose per day. The effects of tadalafil (Cialis) should last for up to 36 hours after a dose. Taking this medication more often can raise your risk for serious side effects, such as priapism or vision changes. If you have questions about your dose of tadalafil (Cialis), talk to your provider.
            Does tadalafil (Cialis) lower blood pressure?
            Yes, because tadalafil (Cialis) works by relaxing your blood vessels, it can lower your blood pressure. But your blood pressure shouldn't drop by too much. In clinical studies, people who took the 20 mg dose of tadalafil (Cialis) experienced an average drop in blood pressure by about 2 mm Hg. Most people won't experience any noticeable symptoms from this blood pressure change. But you might be more sensitive if you're taking other medications that affect your blood pressure (e.g., nitrates, alpha blockers, blood pressure medications). Let your provider know if you feel faint or dizzy after taking tadalafil (Cialis).
            Is it safe to take tadalafil (Cialis) with alcohol?
            Talk to your healthcare provider about drinking alcohol with tadalafil (Cialis). Like tadalafil (Cialis), alcohol can potentially lower your blood pressure. When combined together, your risk for low blood pressure, dizziness, and headache is higher. Additionally, alcohol can make it harder for you to get an erection, which might worsen ED.
            What can I not take with tadalafil (Cialis)?
            You shouldn't take nitrates, which are medications used to treat chest pain, together with tadalafil (Cialis). This combination can cause dangerously low blood pressure. If you do experience chest pain, get medical help right away. Make sure to tell your medical team when you took your last dose of tadalafil (Cialis). This information is important because if medically necessary, your care team can give you a dose of a nitrate if at least 48 hours have passed since your last dose of tadalafil (Cialis). Even then, they must monitor your blood pressure very carefully afterwards. For the same reason, you shouldn't take sGC stimulators, such as Adempas (riociguat). Make sure to discuss all of your medications with your healthcare provider before and after starting tadalafil (Cialis). They can make sure there aren't any potentially dangerous interactions.
            What's the difference between sildenafil (Viagra) and tadalafil (Cialis)?
            Both sildenafil (Viagra) and tadalafil (Cialis) can be used for erectile dysfunction (ED), but there are some differences between them. (1) One difference is that tadalafil (Cialis) is approved to treat both ED and BPH whereas sildenafil (Viagra) can only be used for ED. (2) Another difference is that sildenafil (Viagra) seems to reach its peak effect more quickly, but tadalafil (Cialis) lasts longer. (3) A third difference is that sildenafil (Viagra) can only be used as needed for ED. But you have the option of taking tadalafil (Cialis) every day. Taking a daily dose of tadalafil (Cialis) might be a better option for people who prefer more spontaneity. For more about the differences between sildenafil (Viagra) and tadalafil (Cialis), talk with your provider.
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            What are the risks and warnings for Tadalafil (Cialis)?

            Tadalafil (Cialis) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Heart problems

            • Risk factors: Existing heart condition | Recent heart attack or stroke in past 6 months | High or low blood pressure

              Tell your provider if you have any heart conditions before starting tadalafil (Cialis). Sexual activity isn't recommended for people with certain heart-related conditions, such as very serious heart failure. Tadalafil (Cialis) hasn't been studied in people who have certain conditions, such as recent heart attacks or strokes. If you have a heart condition, talk with your provider about whether tadalafil (Cialis) is safe for you.

              risk-warning

              Low blood pressure

              • Risk factors: Taking alpha blockers | Taking medications for high blood pressure or chest pain (angina) | Drinking alcohol

                If you're taking alpha blockers or medications for high blood pressure with tadalafil (Cialis), your blood pressure may drop too low. Some medications like ritonavir (Norvir) can affect how tadalafil (Cialis) is broken down in your body, which can lead to having too much of it in your system. This can lead to more side effects, like low blood pressure. Your provider might ask you to check your blood pressure regularly if you're taking these other medications. Be very careful getting up from a sitting or lying down position since this can make you feel dizzy and more likely to fall. Drinking alcohol can also cause low blood pressure. Avoid or lower your alcohol consumption when taking tadalafil (Cialis). You should never take tadalafil (Cialis) when taking nitrate medication for chest pain (angina) because it can cause your blood pressure to suddenly drop to unsafe levels.

                risk-warning

                Prolonged erection

                • Risk factors: Medical conditions that affect the penis | Sickle cell anemia | Multiple myeloma | Leukemia

                  Rarely, some people who took tadalafil (Cialis) reported having an erection that lasted for more than 4 hours (priapism). If not treated in time, this can lead to permanent damage to your penis. You're at higher risk for these side effects if you have other conditions affecting your penis, or if you have sickle cell anemia, multiple myeloma, or leukemia. Get medical help right away if you have an erection that lasts longer than 4 hours or if you feel pain during an erection.

                  risk-warning

                  Vision changes

                  • Risk factors: Age 50 years or older | "Crowded" optic disc | Blood vessel problems in the eye

                    If you suddenly notice changes in your vision in one or both eyes, go to the emergency room or call your provider right away. Although rare, tadalafil (Cialis) can cause permanent eye damage. If your provider has told you that you have a "crowded" optic disc, you might be at higher risk for vision changes with tadalafil (Cialis). Tell your provider about your full medical history before taking tadalafil (Cialis).

                    risk-warning

                    Hearing loss

                    Some people who took tadalafil (Cialis) reported experiencing hearing loss. This could happen along with ringing in the ears (tinnitus) and dizziness. Go to the emergency room or call your provider right away if you notice changes in your hearing in one or both ears.

                    risk-warning

                    Interactions with other medications

                    • Risk factors: Age 65 years or older | Liver problems | Kidney problems | Taking nitrate medications | Taking blood pressure medications | Taking alpha blockers | Taking certain antifungals or antivirals

                      Tadalafil (Cialis) can have serious interactions with certain medications. It's important that you tell your provider about all the medications you're taking before you start tadalafil (Cialis). For example, you shouldn't take tadalafil (Cialis) with nitrate medications because this combination can cause your blood pressure to drop dangerously low. If you're taking other blood pressure medications, your provider might not recommend tadalafil (Cialis) until your blood pressure is under control. Taking tadalafil (Cialis) with medications, like oral azole antifungals and ritonavir (Norvir), can put you at higher risk for side effects, such as headaches, flushing, and vision changes.

                      dosage

                      Tadalafil (Cialis) dosage forms

                      The average cost for 90 tablets of 5mg of Tadalafil (Cialis) is $303.20 with a free GoodRx coupon. This is 61.62% off the average retail price of $790.06.
                      tablet
                      Tablet
                      DosageQuantityPrice as low asPrice per unit
                      2.5mg30 tablets$375.11$12.50
                      5mg30 tablets$303.20$10.11
                      10mg30 tablets$1687.03$56.23
                      20mg10 tablets$579.01$57.90

                      Typical dosing for Tadalafil (Cialis)

                      • Erectile dysfunction (taken as needed): The typical starting dose is 10 mg by mouth about 30 minutes before sexual activity up to once per day as needed. Your provider will adjust your dose based on your response.

                      • Erectile dysfunction (taken daily): The typical starting dose is 2.5 mg by mouth at the same time every day, without regard to timing of sexual activity. Your provider will adjust your dose based on your response.

                      • Benign prostatic hyperplasia alone or with erectile dysfunction: The typical dose is 5 mg by mouth at the same time every day.

                      Your dose might differ if you have liver or kidney problems, or if you're taking certain medications.

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                      Reviews

                      Tadalafil (Cialis) Reviews

                      GoodRx has partnered with PatientsLikeMe to provide reviews on the different aspects of Tadalafil (Cialis).

                      Effectiveness

                      Learn more about the effectiveness of Tadalafil (Cialis) based on real life experiences.

                      Overall Rating

                      Based on 34 people taking this medication

                      2.8

                      Effectiveness by condition:

                      erectile dysfunction22 reviews

                      4.3

                      urinary incontinence8 reviews

                      2.8

                      benign prostatic hyperplasia3 reviews

                      1.7

                      median arcuate ligament syndrome1 reviews

                      2.5

                      Side effects
                      Learn more about the side effects others have reported while taking Tadalafil (Cialis).

                      Severity of side effects

                      Based on 65 people taking this medication

                      None

                      60%

                      Mild

                      17%

                      Moderate

                      16%

                      Severe

                      8%

                      0%

                      50%

                      100%

                      Top side effects

                      Based on 65 people taking this medication

                      Headaches

                      8%

                      Sinus congestion

                      5%

                      Pain in lower back

                      5%

                      Chronic headaches

                      4%

                      Allergies

                      2%

                      Usage
                      Review why people stop taking this medication and how long they take it.

                      Reasons people stopped taking Tadalafil (Cialis)

                      Based on 28 people who have taken this medication

                      Expense

                      25%

                      Other

                      25%

                      Did not seem to work

                      22%

                      Change in health plan coverage

                      11%

                      Side effects too severe

                      11%

                      Course of treatment ended

                      4%

                      Doctor's advice

                      4%

                      How long people take Tadalafil (Cialis)

                      Based on 80 people taking this medication

                      Not Specified

                      2%

                      1 to <2 years

                      2%

                      2 to <5 years

                      3%

                      5 to <10 years

                      23%

                      10+ years

                      73%

                      0%

                      50%

                      100%

                      Powered by:Patients Like Me logo
                      interactions

                      Interactions between Tadalafil (Cialis) and other drugs

                      Tadalafil (Cialis) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Tadalafil (Cialis). Please note that only the generic name of each medication is listed below.

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                      Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                      Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                      drug-cost

                      How much does Tadalafil (Cialis) cost?

                      To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                      Cialis (brand)
                      GoodRx lowest price

                      $303.20

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                      contraindications-icon

                      Tadalafil (Cialis) contraindications

                      Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Tadalafil (Cialis) will not be safe for you to take.
                      alternatives

                      What are alternatives to Tadalafil (Cialis)?

                      There are a number of medications that your doctor can prescribe in place of Tadalafil (Cialis). Compare a few possible alternatives below.
                      Tadalafil (Cialis)
                      Used for:

                      • Erectile dysfunction

                      • Benign prostatic hyperplasia (BPH)

                      $303.20 Lowest GoodRx priceView Prices
                      Sildenafil (Viagra)
                      Used for:

                      • Erectile dysfunction (ED)

                      $14.10 Lowest GoodRx priceView Prices
                      Vardenafil
                      Used for:

                      • Erectile dysfunction

                      $34.00 Lowest GoodRx priceView Prices
                      latest news

                      What is the latest news about Tadalafil (Cialis)?

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                      images

                      Tadalafil (Cialis) images

                      Yellow Oval 09 - Tadalafil 5mg Tablet
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                      Yellow Oval B1 And 5 - Tadalafil 5mg Tablet
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                      Yellow Oval 5 And S - Tadalafil 5mg Tablet
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                      Yellow Oval Fj2 - Tadalafil 5mg Tablet
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                      Yellow Round 44 - Tadalafil 5mg Tablet
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                      References

                      Best studies we found

                      Burnett, A. L., et al. (2018). Erectile dysfunction: AUA guideline. The Journal of Urology.

                      Hatzimouratidis, K. (2014). A review of the use of tadalafil in the treatment of benign prostatic hyperplasia in men with and without erectile dysfunction. Therapeutic Advances in Urology.

                      Levine, G. N., et al. (2012). Sexual activity and cardiovascular disease: A scientific statement from the American Heart Association. Circulation.

                      View All References (3)

                      Lupin Pharmaceuticals, Inc. (2023). TADALAFIL tablet, film coated [package insert]. DailyMed.

                      National Institute on Aging. (2020). Prostate problems.

                      Somani, A. N., et al. (2023). Pseudopapilledema.

                      GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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