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Caspofungin

Caspofungin Side Effects

Christina Aungst, PharmDMichelle Nguyen, PharmD
Reviewed by Christina Aungst, PharmD, Michelle Nguyen, PharmD
Last reviewed on March 30, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Fever (20%)
  • Diarrhea (14%)
  • Changes to liver blood tests (12-13%)
  • Low potassium (11%)
  • Chills (10%)
  • Headache (10%)
  • Nausea (9%)
  • Vomiting (8%)
  • Rash (8%)

Less Common Side Effects

  • Swelling of the arms or legs
  • Cough
  • Pneumonia
  • Redness
  • Low blood pressure

Caspofungin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Allergic reactions
  • Life-threatening skin reactions
  • Liver failure

Source: DailyMed

The following Caspofungin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Bloating or swelling of the face, arms, hands, lower legs, or feet

blue lips, fingernails, or skin

blurred vision

changes in skin color

chest pain

confusion

cough

cracked lips

decreased urine

diarrhea

difficult or troubled breathing

difficulty with swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

dry mouth

fever

headache

increased thirst

irregular heartbeat

irregular, fast, slow, or shallow breathing

loss of appetite

mood changes

muscle pain or cramps

nausea

nervousness

numbness or tingling in your hands, feet, or lips

pain or redness at the injection site

pain, tenderness, or swelling of the foot or leg

pale skin

pounding in the ears

rapid weight gain

seizures

slow or fast heartbeat

sneezing

sore throat

sores, ulcers, or white spots on the lips, tongue, or inside the mouth

sweating

tightness in the chest

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

unusual weight gain or loss

vomiting

Less common

Bloody urine

decreased frequency or amount of urine

increased blood pressure

lower back or side pain

weight gain

yellow eyes or skin

Incidence not known

Black, tarry stools

bladder pain

bleeding gums

blood in the urine or stools

bloody nose

chest pain or discomfort

clay-colored stools

cloudy urine

constipation

dark urine

decreased appetite

depression

drowsiness

fever with or without chills

flushed, dry skin

frequent urge to urinate

fruit-like breath odor

general feeling of tiredness or weakness

incoherent speech

increased hunger

increased urination

indigestion

itching

light-colored stools

metallic taste

muscle spasms (tetany) or twitching seizures

muscle weakness

no blood pressure or pulse

noisy, rattling breathing

pain or discomfort in the arms, jaw, back, or neck

pains in the stomach, side, or abdomen, possibly radiating to the back

pinpoint red spots on the skin

rapid weight gain

rash

right upper abdominal or stomach pain and fullness

shakiness in the legs, arms, hands, or feet

stomach pain, continuous

stomach pain or tenderness

stopping of heart

trembling or shaking of the hands or feet

troubled breathing at rest

ulcers, sores, or white spots in the mouth

unconsciousness

unexplained weight loss

unpleasant breath odor

vomiting of blood

weakness

weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Flushing, redness of the skin

unusually warm skin

Incidence not known

Back pain

belching

blistering, peeling, or loosening of the skin

bloated or feeling of fullness

bumps on the skin

difficulty in moving

dry, red, hot, or irritated skin

fear

flaking and falling off of the skin

heartburn

hives or welts

indigestion

joint or muscle pain

lack or loss of strength

muscle pain or stiffness

pressure in the stomach

red skin lesions, often with a purple center

red, irritated eyes

redness of the skin

sleepiness or unusual drowsiness

small red or purple spots on the skin

stomach discomfort, upset, or pain

swelling of the abdominal or stomach area

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Christina Aungst, PharmD, is a pharmacy editor for GoodRx. She began writing for GoodRx Health in 2019, transitioning from freelance writer to editor in 2021.
Michelle Nguyen, PharmD, has been a clinical pharmacist for 6 years (and counting). She has a diverse skill set within managed care pharmacy, specifically in the settings of a medical group, pharmacy benefit manager (PBM), and health plan.

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