CASPOFUNGIN is an antifungal medicine. It is used to treat certain kinds of fungal or yeast infections. Compare echinocandin antifungals.

Caspofungin Side Effects

What should I watch for?

Tell your doctor or health care professional if your symptoms do not improve. During your treatment you will have important lab work done. Follow your doctor's instructions for your care carefully.


Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Bloating or swelling of the face, arms, hands, lower legs, or feet

blue lips, fingernails, or skin

blurred vision

changes in skin color

chest pain



cracked lips

decreased urine


difficult or troubled breathing

difficulty with swallowing

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

dry mouth



increased thirst

irregular heartbeat

irregular, fast, slow, or shallow breathing

loss of appetite

mood changes

muscle pain or cramps



numbness or tingling in your hands, feet, or lips

pain or redness at the injection site

pain, tenderness, or swelling of the foot or leg

pale skin

pounding in the ears

rapid weight gain


slow or fast heartbeat


sore throat

sores, ulcers, or white spots on the lips, tongue, or inside the mouth


tightness in the chest

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

unusual weight gain or loss


Less common

Bloody urine

decreased frequency or amount of urine

increased blood pressure

lower back or side pain

weight gain

yellow eyes or skin

Incidence not known

Black, tarry stools

bladder pain

bleeding gums

blood in the urine or stools

bloody nose

chest pain or discomfort

clay-colored stools

cloudy urine


dark urine

decreased appetite



fever with or without chills

flushed, dry skin

frequent urge to urinate

fruit-like breath odor

general feeling of tiredness or weakness

incoherent speech

increased hunger

increased urination



light-colored stools

metallic taste

muscle spasms (tetany) or twitching seizures

muscle weakness

no blood pressure or pulse

noisy, rattling breathing

pain or discomfort in the arms, jaw, back, or neck

pains in the stomach, side, or abdomen, possibly radiating to the back

pinpoint red spots on the skin

rapid weight gain


right upper abdominal or stomach pain and fullness

shakiness in the legs, arms, hands, or feet

stomach pain, continuous

stomach pain or tenderness

stopping of heart

trembling or shaking of the hands or feet

troubled breathing at rest

ulcers, sores, or white spots in the mouth


unexplained weight loss

unpleasant breath odor

vomiting of blood


weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Flushing, redness of the skin

unusually warm skin

Incidence not known

Back pain


blistering, peeling, or loosening of the skin

bloated or feeling of fullness

bumps on the skin

difficulty in moving

dry, red, hot, or irritated skin


flaking and falling off of the skin


hives or welts


joint or muscle pain

lack or loss of strength

muscle pain or stiffness

pressure in the stomach

red skin lesions, often with a purple center

red, irritated eyes

redness of the skin

sleepiness or unusual drowsiness

small red or purple spots on the skin

stomach discomfort, upset, or pain

swelling of the abdominal or stomach area

trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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