Key takeaways:
The 2025-2026 Moderna COVID-19 vaccines — Spikevax and mNEXSPIKE — are FDA approved for adults ages 65 and older and for younger people at higher risk of severe illness.
You can find Moderna vaccines near you through the online Moderna vaccine locator or by checking with your local pharmacy or health department.
If you’re unsure whether to get vaccinated this season, talk with a healthcare professional. The CDC now recommends making COVID vaccination decisions on an individual basis, depending on your age, health, and risk factors.
The updated Moderna COVID-19 vaccines are two of the four COVID vaccines currently available in the U.S. The updated 2025-2026 versions of these vaccines, called Spikevax and mNEXSPIKE, are designed to work against a subvariant of the virus called LP.8.1. All of the currently available COVID vaccines can help prevent severe illness and hospitalization from COVID.
Below is more information about the updated Moderna vaccine and where to schedule an appointment near you.
Updated Moderna COVID vaccine takeaways
Here’s what you need to know about the updated Moderna COVID vaccines:
Spikevax and mNEXSPIKE are mRNA vaccines that help prevent COVID.
Both Spikevax and mNEXSPIKE are FDA approved for adults ages 65 and older.
For younger people at higher risk of severe COVID, the age cutoffs are different — Spikevax is approved for adults and kids ages 6 months and older, while mNEXSPIKE is approved for those ages 12 years and older.
mNEXSPIKE is sometimes called a “next-generation” COVID-19 vaccine because it takes a more focused approach. Instead of using the full spike protein like Spikevax, it codes for only the most important parts that trigger a strong immune response. This design allows mNEXSPIKE to use a lower mRNA dose (10 mcg versus 50 mcg) while still providing strong protection.
Most people only need 1 dose of Spikevax or mNEXSPIKE for the 2025-2026 season. But some young kids may need 2 doses of Spikevax, depending on their vaccination history.
Some people with a weakened immune system may need more than 1 dose. This depends on your age and vaccination history. Your healthcare professional can tell you how many doses you should receive.
Search and compare options
For more information about COVID vaccines, see:
What to know about updated COVID shots (“COVID booster shots”)
Scheduling your Moderna vaccine appointment
First, find a place to receive your shot. Then make an appointment with that location directly.
You can find Moderna COVID vaccines (Spikevax or mNEXSPIKE) at several local pharmacies. Many major chains, including CVS, Walgreens, and Costco, offer them, as do some grocery stores and independent pharmacies. However, not every location will have both versions available.
To find an updated Moderna vaccine near you, use the online Moderna vaccine locator. You can enter your ZIP code or allow the site to detect your location to see nearby options. Proceed to select your preferred vaccine(s). Availability can vary, so check back often as supplies are updated.
Once you find a location, it’s a good idea to call ahead or check online to confirm that the pharmacy has the updated Moderna vaccine in stock before making an appointment. Inventory can change frequently. You can also contact your local health department to see what’s available near you.
How they compare: Four COVID-19 vaccines are available in the U.S. But is one better than the other for your seasonal shot?
Navigating COVID vaccine updates: As the coronavirus evolves, so do the vaccines. Get the latest updates on COVID vaccine approvals.
Vaccine side effects: Most COVID vaccine side effects are mild and temporary. Here’s what to expect after getting one.
Going beyond vaccines: Discover all you need to know about COVID treatments and preventative medications with our comprehensive guide.
The bottom line
The 2025-2026 Moderna COVID-19 vaccines, called Spikevax and mNEXSPIKE, offer protection against severe illness and hospitalization from COVID. You can schedule an appointment for either vaccine through the Moderna vaccine locator or by contacting your local pharmacy or health department. Because supply can vary, it’s best to confirm that your preferred location has the updated vaccine before you go.
If you’re unsure whether to get vaccinated this season, talk with a healthcare professional. The CDC now recommends making COVID vaccination decisions on an individual basis, taking into account your age, health conditions, and personal risk.
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References
American Academy of Pediatrics. (2025). COVID-19 vaccine frequently asked questions.
Centers for Disease Control and Prevention. (2025). Coronavirus Disease 2019 (COVID-19) vaccine safety.
Centers for Disease Control and Prevention. (2025). Your COVID-19 vaccination.
Ernst, D. (2025). FDA approves Moderna’s next-generation COVID-19 vaccine mNEXSPIKE. Vaccine Advisor.
Medical Letter on Drugs and Therapeutics. (2025). COVID-19 update: mNEXSPIKE — a new Moderna mRNA vaccine for COVID-19.
Moderna. (n.d.). Find a Moderna vaccine near you.
Moderna. (2025). mNEXSPIKE [package insert].
Moderna. (2025). Moderna receives U.S. FDA approval for updated COVID-19 vaccines targeting LP.8.1 variant of SARS-CoV-2. Access Newswire.
Moderna. (2025). Spikevax [package insert].









