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Aplenzin

Aplenzin Side Effects

Robert Chad Hakim, PharmD, BCCCPKristianne Hannemann, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Kristianne Hannemann, PharmD
Last reviewed on October 11, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (26%)
  • Dry mouth (17%)
  • Nausea (13%)
  • Trouble sleeping (11%)
  • Constipation (10%)
  • Dizziness (7%)

Less Common Side Effects

  • Diarrhea
  • Stomach pain
  • Low appetite
  • Anxiety
  • Tremor (shaking)
  • Nervousness
  • Fast heartbeat
  • Sweating
  • Ringing in the ears
  • Muscle pain
  • Rash
  • Sore throat
  • Infection

Note: Side effects are reported from people taking bupropion (Wellbutrin) for depression at the target dose.

Aplenzin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts or behaviors
  • Serious allergic reaction or skin reaction: sore throat, fever, fatigue, rash, hives, painful blisters, skin reddening, skin peeling, swollen lymph nodes, swelling of the face, trouble breathing
  • Seizures

Source: DailyMed

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The following Aplenzin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Anxiety

dry mouth

hyperventilation

irregular heartbeats

irritability

restlessness

shaking

trouble sleeping

Less common

Buzzing or ringing in the ears

headache (severe)

skin rash, hives, or itching

Rare

Confusion

fainting

false beliefs that cannot be changed by facts

having extreme distrust of people

seeing, hearing, or feeling things that are not there

seizures

trouble concentrating

Incidence not known

Actions that are out of control

anger

assaulting or attacking others

being aggressive or impulsive

chest pain or discomfort

fast or pounding heartbeat

force

inability to sit still

need to keep moving

sweating

talking, feeling, or acting with excitement

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Lightheadedness, dizziness, or fainting

loss of consciousness

slow or irregular heartbeat

unusual tiredness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Constipation

decrease in appetite

dizziness

increased sweating

stomach pain

trembling

unusual weight loss

Less common

Blurred vision

change in sense of taste

drowsiness

frequent need to urinate

sore throat

unusual feeling of well-being

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Kristianne Hannemann, PharmD, is a licensed pharmacist in California. She has been a retail pharmacy manager and staff pharmacist for over 7 years and has contributed drug information content to different health companies.

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