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Tamiflu (oseltamivir) is an antiviral medication. More specifically, it's a neuraminidase inhibitor (NAI). Neuraminidase is a protein that's found on the surface of the influenza (flu) virus. It plays a role in helping the virus spread inside someone who's infected. By blocking this protein, Tamiflu (oseltamivir) prevents the flu virus from releasing copies of itself throughout your body and making you feel sicker.