Yes, benzonatate may make some people sleepy. But this is typically mild and doesn't affect everyone who takes the medication. Benzonatate usually causes less drowsiness than prescription cough syrups that contain codeine. When you first start taking benzonatate, it’s a good idea to avoid driving and other activities that require you to be alert. Wait to see how the medication affects you. And avoid other medications and substances that cause drowsiness, such as opioids, benzodiazepines, and alcohol. If you’re only taking benzonatate once a day, try taking it at bedtime. This can help limit coughing in the evening and drowsiness during the day. If you’re taking benzonatate more than once a day and drowsiness is interfering with your daily activities, talk to your prescriber. You may need a lower dosage or a different medication to manage your cough.
View original source